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Current Molecular Therapeutic Agents and Drug Candidates for . | LitMetric

Current Molecular Therapeutic Agents and Drug Candidates for .

Front Pharmacol

Molecular Mechanisms of Antibiotics, Division of Life Science, Department of Bio and Medical Big Data (BK21 Four Program), Research Institute of Life Science, Gyeongsang National University, Jinju, South Korea.

Published: August 2021

AI Article Synopsis

Article Abstract

has been recognised as a dreadful respiratory pathogen among the non-tuberculous mycobacteria (NTM) because of misdiagnosis, prolonged therapy with poor treatment outcomes and a high cost. This pathogen also shows extremely high antimicrobial resistance against current antibiotics, including the anti-tuberculosis agents. Therefore, current chemotherapies require a long curative period and the clinical outcomes are not satisfactory. Thus, there is an urgent need for discovering and developing novel, more effective anti- drugs. In this review, we sum the effectiveness of the current anti- drugs and drug candidates. Furthermore, we describe the shortcomings and difficulties associated with drug discovery and development.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435730PMC
http://dx.doi.org/10.3389/fphar.2021.724725DOI Listing

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