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Purkinje cells located in the adult zebrafish valvula cerebelli exhibit variable functional responses. | LitMetric

AI Article Synopsis

Article Abstract

Purkinje cells are critically involved in processing the cerebellar functions by shaping and coordinating commands that they receive. Here, we demonstrate experimentally that in the adult zebrafish valvular part of the cerebellum, the Purkinje cells exhibited variable firing and functional responses and allowed the categorization into three firing classes. Compared with the Purkinje cells in the corpus cerebelli, the valvular Purkinje cells receive weak and occasional input from the inferior olive and are not active during locomotion. Together, our findings expand further the regional functional differences of the Purkinje cell population and expose their non-locomotor functionality.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443705PMC
http://dx.doi.org/10.1038/s41598-021-98035-3DOI Listing

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