AI Article Synopsis

  • Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an autoimmune disease that leads to nerve damage in the limbs, with symptoms persisting for over two months.
  • A 48-year-old male diagnosed with CIDP experienced muscle weakness and sensory issues, later developing left recurrent nerve palsy signs, including breathy hoarseness and grip strength decline.
  • After high-dose intravenous gamma-globulin therapy, the patient's vocal fold function improved, along with recovery in grip strength and sensory disturbances, normalizing his phonation.

Article Abstract

Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a disease in which peripheral sensory and motor nerves of the four limbs are impaired due to autoimmune mechanism-induced demyelinating changes through a 2-month or longer chronic course. The incidence of complication by cranial neuropathy has been reported to be 15%, but there have been very few reports on disorder of the vagus nerve and its branch, the recurrent nerve. We report a patient who developed left recurrent nerve palsy with CIDP. The patient was a 48-year-old male. The disease developed as progressive muscle weakness and numbness of the four limbs 3 years before and was diagnosed as CIDP. The symptoms had been improved by high-dose intravenous gamma-globulin therapy. However, from 2 months before he became aware of breathy hoarseness, and bilateral decreased grip strength and sensory disturbance of the upper and lower limbs recurred and progressed. On laryngoscopy disorder of left vocal fold movement and glottal closure incompetence during phonation were observed, and neurogenic changes were detected in the left thyroarytenoid muscle by needle electromyography for the intrinsic laryngeal muscles. High-dose intravenous gamma-globulin therapy was performed and left vocal fold movement recovered with recovery of bilateral grip strength and sensory disturbance of the upper and lower limbs, and phonation was also normalized.

Download full-text PDF

Source
http://dx.doi.org/10.1272/jnms.JNMS.2022_89-505DOI Listing

Publication Analysis

Top Keywords

recurrent nerve
12
nerve palsy
8
chronic inflammatory
8
inflammatory demyelinating
8
demyelinating polyradiculoneuropathy
8
high-dose intravenous
8
intravenous gamma-globulin
8
gamma-globulin therapy
8
grip strength
8
strength sensory
8

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!