Poor heat dissipation caused by interface thermal resistance (ITR, or Kapitza resistance) has long been the bottleneck that limits the further miniaturization of integrated circuit. In this paper, different from previous studies on ITR induced by conjunction of two different materials, the ITR of a homogeneous stepped system is studied through the multiparticle Lorentz gas model. It is found that ITR can be triggered by pure geometric shape mismatch, and decreases when the degree of mismatch decreases. The ITRs for forward and backward transport are asymmetrical; thus, thermal rectification effect is also obtained in this system. Moreover, the effects of absolute width, width ratio, mean temperature, and temperature difference on ITR and thermal rectification effect are discussed. The ITR induced by geometric shape mismatch provides physics for interfacial thermal transport.
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http://dx.doi.org/10.1103/PhysRevE.104.024801 | DOI Listing |
Med Chem
January 2025
Department of Pharmacy, Pisa University, Pisa, Italy.
Background: The rise in the frequency of liver cancer all over the world makes it a prominent area of research in the discovery of new drugs or repurposing of existing drugs.
Methods: This article describes the pharmacophore-based structure-activity relationship (3DQSAR) on the secondary metabolites of Alhagi maurorum to inhibit human liver cancer cell lines Hepatocellular carcinoma (HCC) and hepatoma G2 (HepG2) which represents the molecular level understanding for isolated phytochemicals of Alhagi maurorum. The definite features, such as hydrophobic regions, average shape, and active compounds' electrostatic patterns, were mapped to screen phytochemicals.
Soft Robot
January 2025
Department of Mechanical and Nuclear Engineering, Khalifa University of Science and Technology, Abu Dhabi, United Arab Emirates.
Soft robots and bioinspired systems have revolutionized robot design by incorporating flexibility and deformable materials inspired by nature's ingenious designs. Similar to many robotic applications, sensing and perception are paramount to enable soft robots to adeptly navigate the unpredictable real world, ensuring safe interactions with both humans and the environment. Despite recent progress, soft robot sensorization still faces significant challenges due to the virtual infinite degrees of freedom of the system and the need for efficient computational models capable of estimating valuable information from sensor data.
View Article and Find Full Text PDFJ Mater Chem B
January 2025
Department of Optical and Biophysical Systems, Institute of Physics of the Czech Academy of Sciences, Prague, 18200, Czech Republic.
DNA nanostructures (DNs) have gained popularity in various biomedical applications due to their unique properties, including structural programmability, ease of synthesis and functionalization, and low cytotoxicity. Effective utilization of DNs in biomedical applications requires a fundamental understanding of their interactions with living cells and the mechanics of cellular uptake. Current knowledge primarily focuses on how the physicochemical properties of DNs, such as mass, shape, size, and surface functionalization, affect uptake efficacy.
View Article and Find Full Text PDFAnat Rec (Hoboken)
January 2025
Department of Integrative Biology, University of California, Berkeley, California, USA.
The Weberian apparatus is a hearing specialization unique to the otophysan fishes, and an unexpected degree of morphological variation exists in species of the Noturus catfishes. Our aim in this study is to investigate relationships between morphological variations and ecology that may drive this variation. Sampling 48 specimens representing 25 species, we investigated morphological diversity and accounted for ecological variables using landmark-based 3D geometric morphometrics and x-ray-based computed tomography (CT) images.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Sciences, University of Roma Tre, Viale Guglielmo Marconi, Roma, 446 - 00146, Italy.
Sound detection in fishes relies on the inner ear and peripheral structures, such as calcareous otoliths, which play a crucial role in perceiving movement, orientation, and balance. Otoliths, in particular, respond to various environmental factors including temperature, salinity, and food availability, making them valuable indicators of ecological conditions. This study applies geometric morphometrics (GMM) to analyze the otolith shape of Diplodus annularis (Linnaeus, 1758) from two distinct populations located in the Gulf of Asinara (Porto Torres, Sardinia) and the northern Adriatic Sea (Le Tegnue).
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