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Article Synopsis
- Diverse microbial pathogens block host protein synthesis, prompting the host to increase immune gene transcripts in a defensive response that may not always aid survival.
- Research indicates that inhibiting translation initiation improves survival, while inhibiting translation elongation worsens it, revealing contrasting effects on host survival.
- The study highlights the complex roles of translation initiation and elongation in immune responses and host survival during pathogen infections, suggesting distinct mechanisms at play.
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