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The first Italian outbreak of SARS-CoV-2 B.1.1.7 lineage in Corzano, Lombardy. | LitMetric

The first Italian outbreak of SARS-CoV-2 B.1.1.7 lineage in Corzano, Lombardy.

J Med Virol

Section of Microbiology, Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.

Published: January 2022

AI Article Synopsis

Article Abstract

In December 2020, Italy experienced the first case of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) B.1.1.7 lineage. In January 2021, we identified 21 cases of this variant in Corzano, defining the first outbreak of SARS-CoV-2 B.1.1.7 lineage in Italy. The high transmissibility of the B.1.1.7 variant represented an important benefit for the virus, which became rapidly dominant on the territory. Containment measures induced the epidemic curve onto a decreasing trajectory underlining the importance of appropriate control and surveillance for restraint of virus spread. Highlights The first Italian outbreak of SARS-CoV-2 B.1.1.7 lineage occurred in Lombardy in January 2021. The outbreak originated by a single introduction of the B.1.1.7 lineage. The genomic sequencing revealed, for the first time, the presence of the V551F mutation in the B.1.1.7 lineage in Italy. Surveillance, prompt sequencing and tracing efforts were fundamental to identify and to quickly contain the outbreak.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8661962PMC
http://dx.doi.org/10.1002/jmv.27333DOI Listing

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