Arachnoiditis ossificans (AO) is a rare spinal pathology that develops because of bony metaplasia secondary to chronic inflammation. AO may present with debilitating myelopathy secondary to nerve root compression, making it distinct from spinal calcification commonly seen with aging. AO is extremely rare, having been reported less than 100 times, most commonly in the thoracic spine. Even rarer still, AO has been associated with syringomyelia and arachnoid cyst because of associated cerebrospinal fluid (CSF) flow disruption. In this report, we describe a case of AO that presented with right shoulder pain, right-hand numbness, and bilateral lower extremity fatigue who had syringomyelia and arachnoid cyst discovered on MRI imaging. When brought to the operating room for syrinx shunting and cyst fenestration the dural opening was complicated by severe calcification and a diagnosis of AO was made. The patient was treated with partial resection of the calcified plaques. Syringomyelia shunting was abandoned due to low volume. Post-operatively, the patient had improvement in their myelopathy though syrinx was still visualized on follow-up imaging. This report reviews the pathology, clinical and radiographic diagnosis, and treatment strategies for arachnoiditis ossificans.
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http://dx.doi.org/10.7759/cureus.16910 | DOI Listing |
Cureus
September 2024
Internal Medicine, Government Medical College Patiala, Patiala, IND.
Arachnoiditis ossificans (AO) is a rare and complex neurological condition characterized by pathological calcification or ossification of the arachnoid membrane. Arachnoiditis ranks as the third most frequent cause of failed back surgery syndrome (FBSS). This narrative review explores the evolving radiological approaches in its diagnosis and monitoring.
View Article and Find Full Text PDFCureus
September 2023
Department of Neurosurgery, American British Cowdray Neurological Center, Mexico City, MEX.
Arachnoiditis ossificans (AO), a very rare entity that can cause severe neurological deficit, is associated with an inflammatory response and compressive effect on the spinal cord. A 65-year-old woman with diagnosis of arachnoiditis ossificans, who had a past medical history of neurocysticercosis diagnosed eight years before the actual onset that was accompanied by obstructive hydrocephalus and required bilateral ventriculoperitoneal shunts, presented with lower limb paresis. The spinal CT reported large calcified subdural spinal plaques.
View Article and Find Full Text PDFSkeletal Radiol
May 2024
Department of Radiology, Lausanne University Hospital and University of Lausanne, Rue du Bugnon 46, 1011, Lausanne, VD, Switzerland.
AJNR Am J Neuroradiol
February 2023
Department of Radiology and Imaging (C.S.G., J.L.C., S.T.J.), Hospital for Special Surgery, New York, New York
Arachnoiditis ossificans is an uncommon end-stage appearance of chronic adhesive arachnoiditis. Imaging features of arachnoiditis ossificans are characteristic and should be diagnosed to avoid unnecessary intervention and guide prognosis and management. In this case series, we retrospectively analyzed CT and MR imaging of 41 patients to identify common patterns of intrathecal ossification and present the common etiologies.
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