Tricin (3',5'-dimethoxyflavone) is a specialized metabolite which not only confers stress tolerance and involves in defense responses in plants but also represents a promising nutraceutical. Tricin-type metabolites are widely present as soluble tricin -glycosides and tricin-oligolignols in all grass species examined, but only show patchy occurrences in unrelated lineages in dicots. More strikingly, tricin is a lignin monomer in grasses and several other angiosperm species, representing one of the "non-monolignol" lignin monomers identified in nature. The unique biological functions of tricin especially as a lignin monomer have driven the identification and characterization of tricin biosynthetic enzymes in the past decade. This review summarizes the current understanding of tricin biosynthetic pathway in grasses and tricin-accumulating dicots. The characterized and potential enzymes involved in tricin biosynthesis are highlighted along with discussion on the debatable and uncharacterized steps. Finally, current developments of bioengineering on manipulating tricin biosynthesis toward the generation of functional food as well as modifications of lignin for improving biorefinery applications are summarized.
Objectives: Flavonoid compounds exhibit remarkable antioxidant and anti-inflammatory properties in DCM and various other diseases. However, the specific mechanisms by which Tricin, 4',5,7-trihydroxy-3',5'-dimethoxyflavone, exerts its effects in the context of DCM remain to be elucidated.
Methods: Rat H9C2 cells were cultured and subjected to high glucose conditions to establish a DCM cell model.
The use of Bisphenol A (BPA) and its analogs in industries, as well as the products made from them, is becoming a significant concern for human health. Scientific studies have revealed that BPA functions as an endocrine disruptor. While some analogs of BPA (bisphenols) have been used for a longer time, it was later discovered that they are toxic, similar to BPA.
The study focuses on the isolation and purification of tricin, a flavonoid, from the plant Carex Meyeriana Kunth using specific methods like macroporous resins and high-performance liquid chromatography (HPLC).
Among six tested resins, HPD-300 was chosen for its effective adsorption and desorption abilities, allowing tricin's purity to increase significantly through optimized processes, reaching 99.4% purity post-HPLC.
Tricin has anti-cancer properties, showing inhibitory effects on the growth of gastric cancer cells (SGC-7901) by disrupting their cell cycle and energy production processes, suggesting its potential as a therapeutic agent against tumors.
State Key Laboratory of Pollution Control and Resources Reuse, College of Environmental Science and Engineering, Tongji University, Shanghai, 200092, China; Shanghai Urban Pollution Control Engineering Research Center Co., Ltd., 588 Miyun Road, Shanghai, 200092, China. Electronic address:
Alkaline thermal hydrolysis of sewage sludge creates biostimulants that improve plant growth, with this study specifically examining their effects on rice quality in agriculture.
The research found that rice treated with sewage sludge-derived biostimulants (SS-BS) meets safety standards and is enriched with nutrients such as protein and vitamins, enhancing overall quality.
The study also identifies key genes involved in increasing beneficial compounds while inhibiting the synthesis of certain less desirable substances, supporting the idea of SS-BS as a tool for sustainable agriculture and functional food production.
Background: Thinopyrum intermedium (Host) Barkworth & D.R. Dewey, or intermediate wheat grass (IWG), is being developed as the first widely-available perennial grain candidate.
