The objective of this study was to evaluate physical function and health-related quality of life 4 months after the cessation of a 4-month exercise intervention in 89 older adults after discharge from hospital. Linear mixed regression models were used to evaluate between-group differences. Data were analyzed according to the intention-to-treat principle. There was no statistically significant between-group difference in the Short Physical Performance Battery (mean difference 0.5 points, 95% confidence interval [-0.6, 1.5], p = .378). There was a statistically significant difference in favor of the intervention group in functional capacity (the 6-min walk test; mean difference 32.9 m, 95% confidence interval [1.5, 64.3], p = .040) and physical health-related quality of life (physical component summary of medical outcome Study 36-Item Short-Form Health Survey; mean difference 5.9 points, 95% confidence interval [2.0, 9.7], p = .003). Interventions aiming to maintain or increase physical function and health-related quality of life should be encouraged in this population.
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http://dx.doi.org/10.1123/japa.2020-0522 | DOI Listing |
J Clin Med
January 2025
Department of Plastic Surgery, University Hospital Muenster, Waldeyerstrasse 1, 48149 Muenster, Germany.
: Despite its estimated high prevalence among women and increasing awareness, lipedema remains under-investigated. Ignoring its debilitating nature, surgical treatment for this condition is frequently covered by health insurance only in advanced stages and after the exhaustion of conservative therapies. : A total of 1015 patients with lipedema were recruited via social media platforms.
View Article and Find Full Text PDFJ Clin Med
January 2025
Department of Clinical and Biological Sciences, Section of Translational Pharmacology, University of Turin, Regione Gonzole 10, 10043 Orbassano, Italy.
Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease in childhood, leading to severe disability and negatively affecting patients' health-related quality of life (HRQoL). The aim of this systematic review was to evaluate the adoption, reporting and assessment methodology of HRQoL in phase III clinical trials involving children with JIA. An electronic and manual search was conducted to identify primary and secondary publications of pharmacological trials conducted between 2012 and 2023.
View Article and Find Full Text PDFJ Clin Med
December 2024
Unitat de Suport a la Recerca Terres de l'Ebre, Fundació Institut Universitari per a la Recerca al'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), 43500 Tortosa, Spain.
: Multicomponent, non-pharmacological therapies are the preferred first-line treatments for fibromyalgia (FM), but little is known about them in primary care settings. Our study assessed the effectiveness of the FIBROCARE Program in improving the quality of life, functional impact, mood, and pain of people with FM. : We conducted a pragmatic, randomized controlled trial that was not blinded for both patients and the professionals delivering the treatments in the study groups.
View Article and Find Full Text PDFJ Clin Med
December 2024
Heart Center, Sarawak General Hospital, Ministry of Health Malaysia, Kuching 93586, Sarawak, Malaysia.
The HRQ-6D is a newly developed instrument to measure Health-related quality of life (HRQOL) and EQ-5D is the gold standard for measuring HRQOL. This study aims to test the concurrent validity between EQ-5D and HRQ-6D measures among patients with different primary diagnoses. : This cross-sectional study uses two HRQOL measurement instruments, EQ-5D-3L and HRQ-6D.
View Article and Find Full Text PDFCancers (Basel)
January 2025
Department of Haematology and Oncology, University Children's Hospital, Eberhard Karls University Tuebingen, 72076 Tuebingen, Germany.
Background: The incorporation of anti-GD2 antibodies such as ch14.18/SP2/0 into the multimodal treatment of high-risk neuroblastoma (HR-NB) patients has improved their outcomes. As studies assessing the long-term outcomes, long-term sequelae, and health-related quality of life (HRQoL) of this treatment are limited, this retrospective analysis aimed to explore these.
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