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http://dx.doi.org/10.1016/j.molimm.2021.09.003DOI Listing

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A tribute to Nilabh Shastri and a special issue on antigen processing and presentation in Paris (APP10, Paris 2019).

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Institut Necker Enfants Malades, INSERM U1151, CNRS UMR 8253, Université de Paris, F-75015 Paris, France. Electronic address:

The Special Issue is dedicated to the 10th Antigen Processing and Presentation Workshop, which took place at Institut Cochin in Paris from May 28th to June 2nd, 2019. It contains several reviews or original articles from contributors to this workshop. It is also a vibrant Tribute to Nilabh Shastri, founder of the APP Workshops, who untimely passed away in 2021 and is deeply missed by his colleagues and friends.

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mRNA translation from an antigen presentation perspective: A tribute to the works of Nilabh Shastri.

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ICCVS, University of Gdańsk, Science, ul. Wita Stwosza 63, 80-308, Gdańsk, Poland; Inserm UMRS1131, Institut de Génétique Moléculaire, Université Paris 7, Hôpital St. Louis, F-75010, Paris, France; RECAMO, Masaryk Memorial Cancer Institute, Zluty kopec 7, 65653, Brno, Czech Republic; Department of Medical Biosciences, Building 6M, Umeå University, 901 85, Umeå, Sweden. Electronic address:

The field of mRNA translation has witnessed an impressive expansion in the last decade. The once standard model of translation initiation has undergone, and is still undergoing, a major overhaul, partly due to more recent technical advancements detailing, for example, initiation at non-AUG codons. However, some of the pioneering works in this area have come from immunology and more precisely from the field of antigen presentation to the major histocompatibility class I (MHC-I) pathway.

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