Images of the month 1: 'Soy sauce' pleural effusion: what causes black pleural fluid?

Clin Med (Lond)

East and North Hertfordshire NHS Trust, Stevenage, UK.

Published: September 2021

We present a case of black pleural fluid following thoracic trauma. The unusual dark colour most strikingly resembled soy sauce as independently commented upon by multiple treating physicians. The black colouration could not be fully accounted for by haemothorax or cholethorax, so other differential diagnoses were investigated, including infection and malignant melanoma. The cause, however, was thought to be due to staining of the fluid with carbon deposited in the pleural space from the non-volatilised impurities from smoking crack cocaine. A novel use of a point-of-care urine toxicology assay confirmed the presence of cocaine in the pleural fluid. Considering a broad range of differential diagnoses is needed to avoid missing important causes of unusual pleural effusions.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8439504PMC
http://dx.doi.org/10.7861/clinmed.2021-0403DOI Listing

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