Seasonal patterns of water availability can differ dramatically among ecosystems, with well-known consequences for ecosystem structure and functioning. Less appreciated is that climate change can shift the seasonality of water availability (e.g. to wetter springs, drier summers), resulting in both subtle and profound ecological impacts. Here we (1) review evidence that the seasonal availability of water is being altered in ecosystems worldwide, (2) explore several mechanisms potentially driving these changes, and (3) highlight the breadth of ecological consequences resulting from shifts in the seasonality of water availability. We conclude that seasonal patterns of water availability are changing globally, but in regionally specific ways requiring more rigorous and nuanced assessments of ecosystem vulnerability as well as the ecological consequences.
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http://dx.doi.org/10.1111/nph.17728 | DOI Listing |
Mol Pharm
January 2025
Department of Pharmacy, National and Kapodistrian University of Athens, Zografou 15771, Greece.
The simulation of antral conditions for estimating drug apparent equilibrium solubility after a high-calorie, high-fat meal is challenging. In this study, (1) we measured the apparent equilibrium solubility of two model lipophilic drugs, ketoconazole and danazol, in antral aspirates collected at various time points after a minced high-calorie, high-fat meal and a glass of water 30 min after initiation of meal administration, and we designated one point estimate for ketoconazole and one point estimate for danazol; (2) we evaluated the usefulness of FeSSGF-V2 and FEDGAS pH = 3 in reproducing the two point estimates; (3) we evaluated potential compositions of FeSSGF-V3 that simulate the pH, the buffer capacity toward both less acidic and more acidic values, and the antral lipid and protein contents with easily accessible, commercially available products, and (4) we identified the most useful composition of FeSSGF-V3 for reproducing the two point estimates. For both model drugs, apparent solubility in FeSSGF-V2 and in FEDGAS pH 3 deviated substantially from the corresponding point estimate.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
January 2025
Nanjing University of Aeronautics and Astronautics, College of Materials Science and Technology, No. 169 Sheng Tai West Road, Jiangning District, Nanjing, Jiangsu, China, 211106, Nanjing, CHINA.
The neutral oxygen catalysis is an electrochemical reaction of the utmost importance in energy generation, storage application, and chemical synthesis. However, the restricted availability of protons poses a challenge to achieving kinetically favorable oxygen catalytic reactions. Here, we alter the interfacial water orientation by adjusting the Brønsted acidity at the catalyst surface, to break the proton transfer limitation of neutral oxygen electrocatalysis.
View Article and Find Full Text PDFPlant Divers
November 2024
Key Laboratory for Plant Diversity and Biogeography of East Asia, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China.
Leaf nitrogen (N) and phosphorus (P) levels provide critical strategies for plant adaptions to changing environments. However, it is unclear whether leaf N and P levels of different plant functional groups (e.g.
View Article and Find Full Text PDFFront Public Health
January 2025
Johns Hopkins International Injury Research Unit, Health Systems Program, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States.
Background: Drowning is a leading cause of death among young children. The United Nations Resolution on global drowning prevention (2021) and World Health Assembly Resolution in 2023 have drawn attention to the issue. This scoping review synthesizes the current evidence on the effectiveness of child drowning prevention interventions since the 2008 World Report on Child Injury Prevention and implications for their implementation.
View Article and Find Full Text PDFData Brief
February 2025
Toulouse School of Economics, INRAE, University of Toulouse Capitole, 1 Esplanade de l'Université, F31000 Toulouse, France.
Measuring the consumption of processed foods made from a common raw agricultural ingredient requires to make quantities comparable, by converting them in raw product equivalent. This conversion also allows to compute total quantities. In the case of legumes, the challenge is to take into account a wide diversity of final products including packaged dry legumes, processed legumes and products cooked from legumes and other ingredients.
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