Preventing aneuploidy: The groom must wait until the bride is ready.

J Cell Biol

Center for Interdisciplinary Research in Biology, Collège de France, UMR7241/U1050, Paris Sciences et Lettres Research University, Paris, France.

Published: October 2021

Fertilization often triggers the final step of haploidization of the female gamete genome. In this issue, Mori et al. (2021. J. Cell Biol.https://doi.org/10.1083/jcb.202012001) identify two successive actin-dependent mechanisms that delay fusion of maternal and paternal chromosomes, preventing inadvertent elimination of paternal chromosomes together with maternal ones.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438638PMC
http://dx.doi.org/10.1083/jcb.202108030DOI Listing

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