We study the vertical impact of a droplet onto a cubic pillar of comparable size placed on a flat surface, by means of numerical simulations and experiments. Strikingly, during the impact a large volume of air is trapped around the pillar side faces. Impingement upon different positions of the pillar top surface strongly influences the size and the position of the entrapped air. By comparing the droplet morphological changes during the impact from both computations and experiments, we show that the direct numerical simulations, based on the Volume of Fluid method, provide additional and new insight into the droplet dynamics. We elucidate, with the computational results, the three-dimensional air entrapment process as well as the evolution of the entrapped air into bubbles.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429739 | PMC |
| http://dx.doi.org/10.1038/s41598-021-97376-3 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Development and Characterization of Novel Combinations and Compositions of Nanostructured Lipid Carrier Formulations Loaded with Trans-Resveratrol for Pulmonary Drug Delivery.
Pharmaceutics
December 2024
Department of Pharmaceutical Sciences, College of Pharmacy, QU Health Sector, Qatar University, Doha 2713, Qatar.
Background/objectives: This study aimed to fabricate, optimize, and characterize nanostructured lipid carriers (NLCs) loaded with trans-resveratrol (TRES) as an anti-cancer drug for pulmonary drug delivery using medical nebulizers.
Methods: Novel TRES-NLC formulations (F1-F24) were prepared via hot, high-pressure homogenization. One solid lipid (Dynasan 116) was combined with four liquid lipids (Capryol 90, Lauroglycol 90, Miglyol 810, and Tributyrin) in three different ratios (10:90, 50:50, and 90:10 /), with a surfactant (Tween 80) in two different concentrations (0.
Enhanced Stability and In Vitro Biocompatibility of Chitosan-Coated Lipid Vesicles for Indomethacin Delivery.
Pharmaceutics
December 2024
Department of Pharmacology, Faculty of Medicine, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania.
Background: Lipid vesicles, especially those utilizing biocompatible materials like chitosan (CHIT), hold significant promise for enhancing the stability and release characteristics of drugs such as indomethacin (IND), effectively overcoming the drawbacks associated with conventional drug formulations.
Objectives: This study seeks to develop and characterize novel lipid vesicles composed of phosphatidylcholine and CHIT that encapsulate indomethacin (IND-ves), as well as to evaluate their in vitro hemocompatibility.
Methods: The systems encapsulating IND were prepared using a molecular droplet self-assembly technique, involving the dissolution of lipids, cholesterol, and indomethacin in ethanol, followed by sonication and the gradual incorporation of a CHIT solution to form stable vesicular structures.
Living plastics from plasticizer-assisted thermal molding of silk protein.
Nat Commun
January 2025
Department of Biomedical Engineering, Tufts University, Medford, MA, 02155, USA.
The pursuit of materials, particularly plastics, with a minimal ecological footprint throughout their circular lifecycle, is crucial for advancing sustainable materials development. Living materials composed of embedded yet active organisms can leverage endogenous biotic resources to achieve functional materials that align with sustainability goals. However, current living material systems face challenges such as weak mechanical properties, limited environmental adaptability, and restricted cellular functionality.
View Article and Find Full Text PDFNecrotizing fasciitis that led to unexpected and fulminant deterioration in less than 24 hours: a case report.
J Int Med Res
December 2024
Department of Trauma Surgery and Orthopedics, BG Klinikum Duisburg, University Duisburg-Essen, Germany.
Necrotizing fasciitis (NF) is a rapidly progressing condition with a high mortality rate. The poor prognosis is often due to delayed diagnosis, which is typically made clinically or radiologically. This case report highlights a rare instance of fulminant NF with an atypical presentation-no initial clinical signs and an unusual radiological appearance.
View Article and Find Full Text PDFThe buoyancy of cryptococcal cells and its implications for transport and persistence of in aqueous environments.
mSphere
December 2024
Department of Molecular Microbiology and Immunology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA.
Article Synopsis
- Unlabelled is a genus of fungi that can pose health risks to humans and animals, particularly from inhaling spores from soil and trees, and more recently, marine environments.* ! -
- The dynamics of how these fungi spread through water and their buoyancy are not well understood, but recent findings show that salinity affects their ability to stay suspended at the water's surface for extended periods.* ! -
- Cryptococcosis, a serious fungal disease primarily affecting immunocompromised individuals, has increasingly appeared in temperate regions since the 1990s, highlighting the need for further studies on its spread and transport.* !
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!