A method is presented to analyze quantitatively the degree of congenericity of claimed compounds in patent applications. The approach successfully differentiates patents exemplified with highly congeneric compounds of a structurally compact and well defined chemical series from patents containing a more diverse set of compounds around a more vaguely described patent claim. An application to 750 common patents available in SureChEMBL, SureChEMBLccs and ChEMBL is presented and the congenericity of patent compounds in those different sources discussed.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433967 | PMC |
http://dx.doi.org/10.3390/molecules26175253 | DOI Listing |
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