The term inconspicuous penis in children covers both micropenis with a penile length less than 2.5 SD for age and other conditions with a normal length of corpora, but when the penis looks smaller due to other diagnoses. Micropenis in a newborn is a serious condition that needs immediate attention by a paediatric endocrinologist. The boy should have a continuous support until adulthood. Other conditions that resembles micropenis are for example buried or webbed penis that only affects the skin or the adherence of the skin to the penile body, so that penis looks smaller even though the corpora are of normal length. Such conditions are treated and often operated by pediatric urologists. A proper clinical examination distinguishes between these diagnoses and gives a possibility to direct the child to the proper treatment without unnecessary concern for the parents.
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Ann Neurol
January 2025
School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, New South Wales, Australia.
Unlabelled: Congenital titinopathy has recently emerged as one of the most common congenital muscle disorders.
Objective: To better understand the presentation and clinical needs of the under-characterized extreme end of the congenital titinopathy severity spectrum.
Methods: We comprehensively analyzed the clinical, imaging, pathology, autopsy, and genetic findings in 15 severely affected individuals from 11 families.
Rev Sci Instrum
January 2025
National Key Laboratory of Science and Technology on Advanced Laser and High Power Microwave, Institute of Applied Electronics, China Academy of Engineering Physics, Mianyang 621900, China.
The Chinese Academy of Engineering Physics Terahertz Free Electron Laser Facility (CAEP THz FEL, CTFEL) has been operated as a user facility for over five years. To further meet the growing demands of modern science, an upgrade project for an infrared-terahertz free electron laser facility based on CTFEL has been proposed to broaden the frequency range from 0.1-4.
View Article and Find Full Text PDFToxins (Basel)
January 2025
Herpetological Research Center, College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, China.
Chinese coral snakes () are highly neglected regarding their venom profiles and harm to humans, which impedes our ability to deeply understand their biological properties and explore their medicinal potential. In this study, we performed a comparative analysis to reveal the venom profiles of two Chinese coral snakes in terms of their venom yields, proteomic profiles, and immunorecognition by commercial antivenoms. The results showed that expels more venom (lyophilized venom mass) than but possesses a similar solid venom content.
View Article and Find Full Text PDFVet Sci
January 2025
Interdepartmental Centre of Veterinary Radiology, University of Napoli "Federico II", Via Federico Delpino 1, 80137 Napoli, Italy.
The kidney length (KL) to aortic diameter (AoD) ratio (KL/AoD) has been proposed as an ultrasonographic objective method to assess renal dimensions. However, its wide range of normal values limits sensitivity. Of note, its clinical utility in detecting renal disease has not been investigated.
View Article and Find Full Text PDFVet Sci
January 2025
Jockey Club College of Veterinary Medicine and Life Sciences, City University of Hong Kong, Hong Kong SAR 523808, China.
Measuring limb joint angles is crucial for understanding horse conformation, performance, injury diagnosis, and prevention. While Thoroughbred horses have been extensively studied, local Pakistani breeds (e.g.
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