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http://dx.doi.org/10.1097/PRS.0000000000008373 | DOI Listing |
Alzheimers Dement
December 2024
RWJ Barnabas Health, West Orange, NJ, USA.
Background: Effect and Safety of Electroconvulsive Therapy plus Usual Care for the Acute Management of Severe Agitation in Dementia (ECT-AD) is a multi-site NIA-funded FDA-regulated pioneering clinical trial to investigate the effectiveness of electroconvulsive therapy (ECT) in treating severe and treatment-refractory agitation and aggression among individuals with advanced dementia, a condition that has a profound negative impact on patient quality of life and caregiver burden. Here we present baseline demographics of the patient population in this ongoing trial.
Method: To date we have enrolled 18 participants, with a mean age of 74.
Alzheimers Dement
December 2024
Neurobehavioral Systems, Inc, Berkeley, CA, USA.
Background: Paper-and-pencil neuropsychological tests have traditionally been considered the "gold standard" for clinical testing in AD/ADRD, but they have significant limitations: They are time-consuming, costly to administer, vulnerable to examiner bias and error, and unavailable to some patients due to location, transportation challenges, and cost. Manual tests also fail to comprehensively analyze many aspects of test performance. Computerized neuropsychological test batteries have been developed to address these shortcomings.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Federal University of São Carlos, São Carlos, SP, Brazil.
Background: Low- and middle-income countries (LMIC) share characteristics, such as low education, that increase the risk of dementia among their population. Critically, around 70% of the cases of dementia in LMICs are underdiagnosed. Understanding factors contributing to older adults' cognitive performance may support healthcare professionals from these countries in their decision-making process when screening for cognitive decline in their communities.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Helen Wills Neuroscience Institute, University of California, Berkeley, CA, USA.
"Dual Perspectives" integrates multiple MRI scans, creating a nuanced synthesis of grey matter and diffusion-based regional connections. This rendering holds particular significance in the realm of Alzheimer's and dementia research by offering a comprehensive examination of data crucial for understanding these complex neurodegenerative conditions. The inclusion of grey matter provides a detailed insight into the structural composition of the brain.
View Article and Find Full Text PDFAnn Med
December 2025
Department of Nursing, Faculty of Health Sciences of Ceuta, University of Granada, Ceuta, Spain.
Objective: To establish a new technique to easily identify the fetal cervix-uterus complex in normal female fetuses from 20 to 40 weeks of gestation.
Material And Methods: The study was performed in routine examination in normal fetuses by two observers. Twenty-five consecutive cases per gestational week were assessed between 20 and 40 weeks.
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