AI Article Synopsis
- DDR1 is a key protein in the receptor tyrosine kinase family that is linked to tumor invasion, metastasis, and the development of conditions like inflammation and fibrosis.
- Abnormal activation of DDR1 can contribute to cancer progression by affecting cell behaviors such as adhesion, migration, and cytokine secretion, which are essential for various bodily functions.
- The review highlights recent research on DDR1's role in breast cancer and other tumors to offer insights for future prevention and treatment strategies.
Article Abstract
Discoidin domain receptor 1(DDR1)is a critical member of the receptor tyrosine kinase family.It may be related to tumor invasion and metastasis,and the abnormal activation of DDR1 can lead to the occurrence and development of malignant tumors,inflammation,and fibrosis.DDR1 are involved in cell adhesion,migration,proliferation,secretion of cytokines,and remodeling of extracellular matrix,thus playing a critical role in various pathophysiological processes of the human body.In this review,we demonstrate the research progress of DDR1 in breast cancer and other malignant tumors,in order to provide a new theoretical basis for the prevention and treatment of breast cancer and other tumors.
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| http://dx.doi.org/10.3881/j.issn.1000-503X.13315 | DOI Listing |
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