Trimester-Specific Association of Maternal Exposure to Fine Particulate Matter and its Components With Birth and Placental Weight in Japan.

Yuki Takeda Takehiro Michikawa Seiichi Morokuma Shin Yamazaki Kazushige Nakahara Ayako Yoshino Seiji Sugata Akinori Takami Shinji Saito Junya Hoshi Kiyoko Kato Hiroshi Nitta Yuji Nishiwaki

J Occup Environ Med

Department of Environmental and Occupational Health, Toho University Graduate School of Medicine, 5-21-16 Omori-nishi, Ota-ku, Tokyo 143-8540, Japan (Dr Takeda, Dr Michikawa, and Dr Nishiwaki); Department of Environmental and Occupational Health, School of Medicine, Toho University, 5-21-16 Omori-nishi, Ota-ku, Tokyo 143-8540, Japan (Dr Michikawa and Dr Nishiwaki); Department of Health Sciences, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan (Dr Morokuma); Health and Environmental Risk Division, National Institute for Environmental Studies, 16-2 Onogawa, Tsukuba, Ibaraki 305-8506, Japan (Dr Yamazaki and Dr Nitta); Department of Obstetrics and Gynaecology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan (Dr Nakahara and Dr Kato); Regional Environment Conservation Division, National Institute for Environmental Studies, 16-2 Onogawa, Tsukuba, Ibaraki 305-8506, Japan (Dr Yoshino, Dr Sugata, and Dr Takami); Tokyo Metropolitan Research Institute for Environmental Protection, 1-7-5 Shinsuna, Koto-ku, Tokyo 136-0075, Japan (Dr Saito and Dr Hoshi).

Published: September 2021

Objective: We investigated which trimester of exposure to PM2.5 and its components was associated with birth and placental weight, and the fetoplacental weight ratio.

Methods: The study included 63,990 women who delivered singleton term births within 23 Tokyo wards between 2013 and 2015. Each day, we collected fine particles on a filter, and analyzed their chemical constituents, including carbons and ions. Trimester-specific exposure to each pollutant was estimated based on the average daily concentrations.

Results: Over the third trimester, sulfate exposure tended to be inversely associated with birth weight, and decreased placental weight (difference for highest vs lowest quintile groups = -6.7 g, 95% confidence interval = -12.5 to -0.9). For fetoplacental weight ratio, there was no relationship.

Conclusions: Sulfate exposure over the third trimester may reduce birth weight, particularly placental weight.

Download full-text PDF	Source
http://dx.doi.org/10.1097/JOM.0000000000002254	DOI Listing

Publication Analysis

Top Keywords

placental weight

birth placental

weight

associated birth

fetoplacental weight

third trimester

sulfate exposure

birth weight

exposure

trimester-specific association

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!