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http://dx.doi.org/10.1111/1346-8138.16138 | DOI Listing |
Skinmed
December 2024
Serviço de Dermatologia, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil.
Nat Commun
January 2025
Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.
Key functions of antibodies, such as viral neutralisation, depend on high-affinity binding. However, viral neutralisation poorly correlates with antigen affinity for reasons that have been unclear. Here, we use a new mechanistic model of bivalent binding to study >45 patient-isolated IgG1 antibodies interacting with SARS-CoV-2 RBD surfaces.
View Article and Find Full Text PDFSAGE Open Med Case Rep
December 2024
Department of Dermatology, College of Medicine, University of Saskatchewan, Regina, SK, Canada.
We report a 56-year-old male who developed cutaneous lichen planus (LP) following Vaxzevria (Oxford-AstraZeneca) COVID-19 vaccination. Multiple topical and systemic therapies were tried with limited success; however, partial improvement was observed with narrow-band UVB (NB-UVB) phototherapy. This report adds to the growing evidence of new-onset LP following COVID-19 vaccination and underscores the need for careful reporting, monitoring, and management of vaccine-related adverse effects.
View Article and Find Full Text PDFRev Med Inst Mex Seguro Soc
September 2024
Instituto Mexicano del Seguro Social, Unidad de Medicina Familiar No. 55, Servicio de Medicina Familiar. Puebla, Puebla, México.
Background: COVID-19 is a severe acute respiratory syndrome caused by SARS-CoV-2. This disease had a high mortality rate and turned into a pandemic, which is why it was considered a severe public health problem. In this context, pregnant patients were a vulnerable group and, consequently, an effective vaccine was necessary.
View Article and Find Full Text PDFCureus
October 2024
Department of Biomedical Sciences, College of Medicine, University of Zakho, Zakho Duhok, IRQ.
Background And Aim: The COVID-19 pandemic has profoundly impacted global health, necessitating the rapid development of vaccines to reduce its effects. However, concerns among healthcare workers regarding vaccine safety and side effects have led to increased hesitancy towards COVID-19 vaccination. Therefore, this study aims to assess the severity of adverse effects and associated factors of three COVID-19 vaccines among healthcare workers in Iraqi Kurdistan.
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