AI Article Synopsis
- Supramolecular chemistry offers innovative methods for recognizing, isolating, and controlling proteins, which is valuable for research and therapeutic applications.
- By utilizing techniques like genetic-code expansion and enzyme-mediated ligation, researchers can incorporate specific recognition elements into target proteins, enabling precise functional regulation.
- The article will explore various methods, their applications, challenges, and future directions in the field of protein-targeting supramolecular chemistry.
Article Abstract
Supramolecular chemistry for targeting proteins is of great interest for the development of novel approaches to recognize, isolate and control proteins. Taking advantage of chemical biology approaches, such as genetic-code expansion and enzyme-mediated ligation, guest recognition elements can be built into proteins of interest, allowing supramolecular control of protein function and regulation. In this viewpoint article, we will discuss the methods, applications, limitations, and future perspectives of supramolecular chemistry for targeting proteins in a site-specific manner.
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| http://dx.doi.org/10.1002/cbic.202100357 | DOI Listing |
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