Hormone resistance in children: what primary care physicians need to know.

Acta Biomed

Department of Pediatrics, Faculty of Medicine, Assiut University, Assiut, Egypt..

Published: September 2021

AI Article Synopsis

  • Hormone resistance occurs when target tissues do not respond properly to hormones, which can result from either too little or too much hormone.
  • Several disorders are related to hormone resistance, including Laron syndrome, insulin resistance, and androgen insensitivity syndrome, among others.
  • The article aims to provide primary care physicians with essential information on how to recognize, diagnose, and manage hormone resistance disorders in children.

Article Abstract

Hormone resistance is defined as a reduced or absence of  target tissues responsiveness to a hormone, where the presentation is related to either a relative lack or excess of hormones. Various disorders of hormone resistance were encountered including, Laron syndrome, nephrogenic diabetes insipidus, thyroid hormone resistance syndrome, pseudohypoparathyroidism, insulin resistance, familial glucocorticoid deficiency, pseudohypoaldosteronism, X linked hypophosphatemic rickets  and androgen insensitivity syndrome. The article gives a summary that presents, in concentrated form, what the primary care physicians need to know about recognition,  clinical presentation, diagnosis, and management  of various hormone resistance in children.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477115PMC
http://dx.doi.org/10.23750/abm.v92i4.11613DOI Listing

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