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Use of biochemical and imaging criteria for selecting patients for prostate biopsy in recurrence risk assessment post-HIFU therapy.
World J Urol
March 2025
Desai Sethi Urology Institute, University of Miami, Miller School of Medicine, Miami, FL, USA.
Purpose: Despite the growing adoption of HIFU treatment for localized prostate cancer (PC), standardized criteria for evaluating success and predicting recurrence remain undefined. Herein, we analyze the predictive value of noninvasive tools such as PSA dynamics and MRI to determine recurrence.
Methods: We identified from our HIFU therapy prospective registry patients who developed biopsy-proven recurrence, between 2016 and 2023.
The presence of prostate MRI-visible lesions at follow-up biopsy as a risk factor for histopathological upgrading during active surveillance.
Abdom Radiol (NY)
March 2025
Universidade de São Paulo, São Paulo, Brazil.
Objective: To prospectively determine the ability of visible lesions on multiparametric MRI (PI-RADS 4-5) and commonly used biomarkers to predict disease upgrading on rebiopsy in men with low-risk prostate cancer (PCa) enrolled in active surveillance (AS).
Materials And Methods: For this prospective study, approved by the Institutional Review Board (IRB), we selected consecutive patients with low-risk, low-grade, and localized prostate cancer (PCa) from our active surveillance (AS) program, who were enrolled between March 2014 and December 2020. Patients who had undergone previous prostate surgery, hormonal treatment, had contraindications for mpMRI, or transrectal ultrasound-guided (TRUS) biopsy were excluded from this study.
Safety and Efficacy Clinical Trial of Robot-Assisted Prostate Biopsy Using a Hand-Held Robotic System.
Int J Med Robot
April 2025
State Key Laboratory of Robotics and System, Department of Mechanical Engineering, Harbin Institute of Technology, Harbin, China.
Background: Robotic systems are increasingly utilised to improve clinical outcomes in prostate interventions.
Methods: We enroled 20 patients to verify the clinical feasibility of transrectal ultrasound (TRUS)-guided robot-assisted prostate biopsy (PBx). For each patient, controlled trials of systematic 12-core PBx were initially conducted manually using a biopsy gun, followed by a 3-core cognitive fusion targeted biopsy performed by the hand-held robot.
Clinical predictors of bladder outlet obstruction in men consulting for routine urological screening.
Int Urol Nephrol
March 2025
Division of Experimental Oncology/Unit of Urology, URI, IRCCS Ospedale San Raffaele, Via Olgettina 60, 20132, Milan, Italy.
Purpose: Lower urinary tract symptoms (LUTS) associated with bladder outlet obstruction (BOO) are prevalent among men, notwithstanding being self-underreported. We aimed to assess the predictors for BOO during first visit.
Methods: Data from 1045 analyzed men older than 40 years attending a single urological institution from 2010 to 2021.
Developing a training for 3D transrectal multiparametric ultrasound of the prostate: a human factors engineering approach.
Expert Rev Med Devices
March 2025
Department of Urology, Amsterdam UMC, Location VUmc, Amsterdam, The Netherlands.
Objective: Three-dimensional multiparametric ultrasound (3D mpUS) shows promise for accurately diagnosing prostate cancer. However, its technical complexity presents usability challenges. Human Factor Engineering (HFE) studies the interaction between devices and users, by reducing human error, increasing productivity, and enhancing safety.
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