Bacterial DNA screening to characterize surgical site infection risk in orthopaedic patients.

J Orthop

University of Missouri, Thompson Laboratory for Regenerative Orthopaedics, Missouri Orthopaedic Institute, 1100 Virginia Ave., Columbia, MO, 65212, USA.

Published: August 2021

Purpose: To provide an initial characterization of relevant bacterial DNA profiles for patients undergoing closed-fracture fixation or total joint arthroplasties.

Patients And Methods: Swabs were collected and analyzed using Polymerase Chain Reaction from adult patients undergoing closed-fracture fixation or total shoulder, knee, or hip arthroplasties.

Results: Bacterial DNA profiles varied across the different orthopaedic patient populations, and produced uncharacteristic profile shifts with direct relevance to each clinical infection.

Conclusion: Findings provide a foundational dataset regarding bacterial colonization of relevant anatomic sites that can act as sources of surgical site infections for patients.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403679PMC
http://dx.doi.org/10.1016/j.jor.2021.08.012DOI Listing

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