Background: Allergic reactions are common symptoms in the emergency department (ED), with anaphylaxis comprising 1-3% of ED visits. Anaphylaxis is a clinical diagnosis. Treatment of anaphylaxis starts with airway, oxygenation, and decontamination, followed by medication administration.
Case Report: We describe a patient who presented to the ED with anaphylaxis complicated by a persistent exposure to the allergen with need for emergent decontamination. Why Should an Emergency Physician be Aware of This? Knowing the treatment of anaphylaxis is critical to prevent morbidity and mortality. This case is a reminder to always remove the offending agent and nuances involved with treating critically ill pregnant patients.
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http://dx.doi.org/10.1016/j.jemermed.2021.07.032 | DOI Listing |
J Dtsch Dermatol Ges
January 2025
Department of Dermatology and Allergology, University Hospital Marburg, Philipps University Marburg, Marburg, Germany.
Vaccination is a fundamental principle of preventive health care. Administration of the vaccine, which contains the antigen(s) of a pathogen, activates the immune system and provides protection against infection. The immunogenicity and allergenicity of a vaccine may lead to various adverse reactions, depending on the responsiveness and susceptibility of the vaccinated individual.
View Article and Find Full Text PDFFoods
January 2025
Department of Immunology and Allergy, Medical University of Lodz, 90-419 Lodz, Poland.
According to projections by the Food and Agriculture Organization of the United Nations, the global population will reach 9 billion by 2050. This raises concerns about the ability to feed such a population. In view of the above, it is necessary to search for alternative food sources.
View Article and Find Full Text PDFMedicine (Baltimore)
January 2025
Shanxi Provincial Integrated TCM and WM Hospital, Taiyuan, China.
Rationale: Local anesthesia is a widely used technique for emergency wound closure, with lidocaine among the most commonly employed local anesthetics. Allergic reactions to lidocaine are rare, with anaphylaxis being even more uncommon.
Patient Concerns And Diagnosis: This report describes a 72-year-old male patient who presented with a right foot injury and underwent wound suturing under lidocaine local anesthesia.
Vaccines (Basel)
December 2024
Department of Biochemistry, College of Natural Sciences, Kangwon National University, Chuncheon 24341, Republic of Korea.
Messenger RNA (mRNA)-based therapeutics have shown remarkable progress in the treatment and prevention of diseases. Lipid nanoparticles (LNPs) have shown great successes in delivering mRNAs. After an mRNA-LNP vaccine enters a cell via an endosome, mRNA is translated into an antigen, which can activate adaptive immunity.
View Article and Find Full Text PDFIntroduction: Limited research is available regarding recommendations about which drug allergy alerts (DAAs) in clinical decision support (CDS) systems should interrupt provider workflow. The objective was to evaluate the frequency of penicillin and cephalosporin DAA overrides at two institutions. A secondary objective was to redesign DAAs using a new tiered alerting system based on patient factors.
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