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| http://dx.doi.org/10.1161/JAHA.121.023189 | DOI Listing |
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What Is Normal Growth? Principles, Practicalities and Pitfalls of Growth Assessments in Infants and Children.
Ann Nutr Metab
November 2024
Community Health Sciences, O'Brien Institute of Public Health, Alberta Children's Hospital Research Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Background: Growth assessments are a pillar of public health surveillance, individual health screening, and clinical care. Normal growth is defined differently for individuals versus populations. The World Health Organization (WHO) growth standards were developed to describe the pattern of growth in healthy children without socioeconomic limitations whose mothers planned to breastfeed.
View Article and Find Full Text PDFThe Oxygen Cascade According to HFpEF Likelihood: A Focus on Sex Differences.
JACC Adv
July 2024
Department of Cardiology, JESSA Hospital, Hasselt, Belgium.
Background: Women are at greater risk for heart failure with preserved ejection fraction (HFpEF).
Objectives: The aim of the study was to compare sex differences in the pathophysiology of exertional breathlessness in patients with high vs low HFpEF likelihood.
Methods: This cohort study evaluated consecutive patients (n = 1,936) with unexplained dyspnea using cardiopulmonary exercise testing and simultaneous echocardiography and quantified peak oxygen uptake (peak VO) and its determinants.
Article Synopsis
- Half of the heart failure patients with preserved ejection fraction (HFpEF) remain undiagnosed with just resting evaluations, leading researchers to suggest exercise testing as a potential solution.
- A study involving 1,936 patients evaluated their exercise performance and the mean pulmonary artery pressure over cardiac output (mPAP/CO) slope to assess their HFpEF likelihood.
- Results indicated that 22% of patients had abnormal test results with a high mPAP/CO slope despite a negative diastolic stress test (DST), suggesting that this slope could be a key indicator of HFpEF, even when DST results are not conclusive.
Impact of foot progression angle on spatiotemporal and plantar loading pattern in intoeing children during gait.
Sci Rep
June 2024
School of Medical Imaging, Xuzhou Medical University, Xuzhou, China.
Intoeing in children is a common parental concern, but our understanding of the impact of foot progression angle (FPA) in these children leaves remains limited. This study examines the relationship between FPA and plantar loading pattern, as well as gait symmetry in children with intoeing. The sample included 30 children with intoeing caused by internal tibial torsion, uniformly divided into three groups: unilateral intoeing, bilateral mild intoeing, and bilateral mild-moderate intoeing.
View Article and Find Full Text PDFmPAP/CO Slope and Oxygen Uptake Add Prognostic Value in Aortic Stenosis.
Circulation
April 2024
Departments of Cardiology (S.H., J.S., M.F., S.M.F., G.C., L.H., J.V.), Jessa Hospital, Hasselt, Belgium.
Background: Recent guidelines redefined exercise pulmonary hypertension as a mean pulmonary artery pressure/cardiac output (mPAP/CO) slope >3 mm Hg·L·min. A peak systolic pulmonary artery pressure >60 mm Hg during exercise has been associated with an increased risk of cardiovascular death, heart failure rehospitalization, and aortic valve replacement in aortic valve stenosis. The prognostic value of the mPAP/CO slope in aortic valve stenosis remains unknown.
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