The objective of the current study was to design and build a dual-tuned coil array for simultaneous Na/ H MRI of the human brain at 7 T. Quality factor, experimental B measurements, and electromagnetic simulations in prototypes showed that setups consisting of geometrically interleaved H and Na loops performed better than or similar to H or Na loops in isolation. Based on these preliminary findings, we built a transmit/receive eight-channel Na loop array that was geometrically interleaved with a transmit/receive eight-channel H loop array. We assessed the performance of the manufactured array with mononuclear signal-to-noise ratio (SNR) and B measurements, along with multinuclear magnetic resonance fingerprinting maps and images. The Na array within the developed dual-tuned device provided more than 50% gain in peripheral SNR and similar B uniformity and coverage as a reference birdcage coil of similar size. The H array provided good B uniformity in the brain, excluding the cerebellum and brain stem. The integrated Na and H arrays were used to demonstrate truly simultaneous quantitative H mapping and Na imaging.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9362999 | PMC |
| http://dx.doi.org/10.1002/nbm.4608 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Computational Design of a Thermal Applicator for Brain Hyperthermia Controlled by Capacitor Positioning in Loop Coils.
Magn Reson Med Sci
January 2025
Department of Biomedical Engineering, Gachon University, Seongnam, Gyeonggi, Korea.
Purpose: Hyperthermia is a treatment that applies heat to damage or kill cancer cells and can be also used for drug deliveries. It is important to apply the heat into the specific area in order to target the cancer tissue and avoid damaging healthy tissue. For this reason, the development of heat applicators that have the capability to deliver the heat to the target area is vital.
View Article and Find Full Text PDFUltrafast dynamic contrast-enhanced breast MRI with quantitative perfusion parameters in differentiating breast cancer: a study focusing on triple-negative and HER2 positive breast cancer.
Front Oncol
January 2025
Department of Radiology, the Second Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Background: In the realm of breast cancer diagnosis and treatment, accurately discerning molecular subtypes is of paramount importance, especially when aiming to avoid invasive tests. The updated guidelines for diagnosing and treating HER2 positive advanced breast cancer, as presented at the 2021 National Breast Cancer Conference and the Annual Meeting of the Chinese Society of Clinical Oncology, highlight the significance of this approach. A new generation of drug-antibody combinations has emerged, expanding the array of treatment options for HER2 positive advanced breast cancer and significantly improving patient survival rates.
View Article and Find Full Text PDFOmnidirectional Wireless Power Transfer for Millimetric Magnetoelectric Biomedical Implants.
IEEE J Solid-State Circuits
November 2024
Department of Electrical and Computer Engineering, Rice University, Houston TX, 77005, USA.
Miniature bioelectronic implants promise revolutionary therapies for cardiovascular and neurological disorders. Wireless power transfer (WPT) is a significant method for miniaturization, eliminating the need for bulky batteries in today's devices. Despite successful demonstrations of millimetric battery-free implants in animal models, the robustness and efficiency of WPT are known to degrade significantly under misalignment incurred by body movements, respiration, heart beating, and limited control of implant orientation during surgery.
View Article and Find Full Text PDFEnhancing fine-tuning efficiency and design optimization of an eight-channel 3T transmit array via equivalent circuit modeling and Eigenmode analysis.
Med Phys
January 2025
Department of Electrical and Electronics Engineering, Bilkent University, Ankara, Turkey.
Background: Radiofrequency (RF) transmit arrays play a crucial role in various MRI applications, offering enhanced field control and improved imaging capabilities. Designing and optimizing these arrays, particularly in high-field MRI settings, poses challenges related to coupling, resonance, and construction imperfections. Numerical electromagnetic simulation methods effectively aid in the initial design, but discrepancies between simulated and fabricated arrays often necessitate fine-tuning.
View Article and Find Full Text PDFArticle Synopsis
- Multichannel transceiver coil arrays are essential for enhancing parallel imaging and B1 manipulation in ultrahigh field MR imaging and spectroscopy, but designing them poses challenges related to high frequency operation and electromagnetic decoupling.
- This study introduces a high impedance microstrip transmission line resonator (HIMTL) technique that addresses these challenges by providing high frequency capability and sufficient EM decoupling without extra circuits.
- A two-channel array was created for a 10.5T application, tuned to the proton Larmor frequency of 447 MHz, and tests showed that the HIMTL technique is a viable solution for developing high performance transceiver coils for ultrahigh field MR imaging.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!