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and Extracts Recover Functional Blood Hemoglobin Derivatives in Rabbits Exposed to High Altitude.
Curr Pharm Biotechnol
August 2022
High Altitude Research Center, Prince Sultan Medical Complex, Al-Hawiyah, Taif University, Taif, Saudi Arabia.
Background: Shortage of oxygen is a common condition for residents of high-altitude (HA) areas. In mammals, hemoglobin (Hb) has four derivatives: oxyhemoglobin (Hb-O), carboxyhemoglobin (Hb-CO), sulfhemoglobin (Hb-S), and methemoglobin (Met-Hb). In HA areas, aberrant physiological performance of blood hemoglobin is well-established.
View Article and Find Full Text PDFSynthesis and utilization of CoO doped carbon nanofiber for fabrication of hemoglobin-based electrochemical sensor.
Mater Sci Eng C Mater Biol Appl
February 2020
Key Laboratory of Laser Technology and Optoelectronic Functional Materials of Hainan Province, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou, 571158, PR China. Electronic address:
In this paper cobalt oxide (CoO) nanoparticles were mixed with polyacrylonitrile to prepare CoO doped carbon nanofiber (CNF) composite by electrospinning and carbonization, which was further used to modify on carbon ionic liquid electrode (CILE). Hemoglobin (Hb) was immobilized on CoO-CNF/CILE surface with Nafion acted as the protective film to fabricate an electrochemical biosensor (Nafion/Hb/CoO-CNF/CILE). Electrochemical behavior of Hb on the electrode was investigated with a pair of quasi-reversible redox peak appeared on cyclic voltammogram and electrochemical parameters were calculated.
View Article and Find Full Text PDFInfrared absorption study of the heme pocket dynamics of carbonmonoxyheme proteins.
Biophys J
December 2006
Department of Biophysics and Radiation Biology, Semmelweis University, Budapest, Hungary.
The temperature dependencies of the infrared absorption CO bands of carboxy complexes of horseradish peroxidase (HRP(CO)) in glycerol/water mixture at pH 6.0 and 9.3 are interpreted using the theory of optical absorption bandshape.
View Article and Find Full Text PDF[Study on mechanism of different PHAs during heating by FTIR].
Guang Pu Xue Yu Guang Pu Fen Xi
October 2000
Department of Chemistry, Tsinghua University, 100084 Beijing.
In this paper, PHB, P(HO-co-HD), a various composition of P(HB-co-HV) copolymer and P(HB-co-HH) copolymer were studied both at normal temperature and in the process of increasing and decreasing temperature using FTIR spectroscopy technology. Results showed that FTIR spectra of PHAs with various compositions have distinguishing characteristics. Physical transformation occurred when PHAs were treated with heat denaturalization, and this physical process was reversible.
View Article and Find Full Text PDFIncreased blood carboxyhaemoglobin concentrations in inflammatory pulmonary diseases.
Thorax
September 2002
Department of Geriatric and Respiratory Medicine, Tohoku University School of Medicine, Sendai 980-8574, Japan.
Background: Exhaled carbon monoxide has been reported to increase in inflammatory pulmonary diseases and to be correlated with blood carboxyhaemoglobin (Hb-CO) concentration. A study was undertaken to determine whether arterial blood Hb-CO increases in patients with inflammatory pulmonary diseases.
Methods: The Hb-CO concentration in arterial blood was measured with a spectrophotometer in 34 normal control subjects, 24 patients with bronchial asthma, 52 patients with pneumonia, and 21 patients with idiopathic pulmonary fibrosis (IPF).
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