AI Article Synopsis
- Corticosteroid injections (CSIs) are frequently used to treat carpal tunnel syndrome, but recent studies have raised concerns about their association with a higher risk of postoperative infections in orthopedic surgeries.
- A study conducted from 2010 to 2019 analyzed patients who underwent carpal tunnel release (CTR) and found that those who received preoperative CSIs had a significantly higher rate of postoperative infections compared to those who did not.
- The research revealed that 41% of patients with infections had received a CSI prior to surgery, suggesting a link between the timing of the injection and the infection risk, although further investigation is needed to explore other contributing factors like dosage and patient comorbidities.
Article Abstract
Purpose: Corticosteroid injections (CSIs) are commonly used in carpal tunnel syndrome; however, recent literature has demonstrated risk of postoperative infection associated with preoperative CSIs in other orthopedic fields. The aim of this study was to assess the relationship of CSIs and postoperative infection following carpal tunnel release (CTR).
Methods: A single-center retrospective review was conducted from 2010 to 2019 to identify patients who underwent CTR with subsequent antibiotic prescription for chart-documented wound infection. A demographically-matched cohort of 100 patients was identified for comparison. Information on patient demographics, comorbidities, injection history, and presence of postoperative infection was collected.
Results: Thirty-nine patients (0.67% of all CTR patients) were identified with postoperative infections, 3 of which (0.05% of all CTR patients) were deep infections. In the infection cohort, 16 of 39 (41%) patients received an injection prior to surgery, whereas 16 of 100 (16%) patients in the control cohort received an injection. History of CSI was significantly more common in patients with postoperative infection, and patients in the infection cohort had a significantly shorter average time from injection to surgery by approximately 55 days.
Conclusions: Corticosteroid injections in the preoperative period are associated with postoperative infection after CTR. Proximity of injection to time of surgery plays a role, although comorbidities, the corticosteroid dose, and frequency of injection require further study to determine risk contribution.
Type Of Study/level Of Evidence: Prognostic III.
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| http://dx.doi.org/10.1016/j.jhsa.2021.06.022 | DOI Listing |
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