There has been a recent surge of success in optimizing deep reinforcement learning (DRL) models with neural evolutionary algorithms. This type of method is inspired by biological evolution and uses different genetic operations to evolve neural networks. Previous neural evolutionary algorithms mainly focused on single-objective optimization problems (SOPs). In this article, we present an end-to-end multi-objective neural evolutionary algorithm based on decomposition and dominance (MONEADD) for combinatorial optimization problems. The proposed MONEADD is an end-to-end algorithm that utilizes genetic operations and rewards signals to evolve neural networks for different combinatorial optimization problems without further engineering. To accelerate convergence, a set of nondominated neural networks is maintained based on the notion of dominance and decomposition in each generation. In inference time, the trained model can be directly utilized to solve similar problems efficiently, while the conventional heuristic methods need to learn from scratch for every given test problem. To further enhance the model performance in inference time, three multi-objective search strategies are introduced in this work. Our experimental results clearly show that the proposed MONEADD has a competitive and robust performance on a bi-objective of the classic travel salesman problem (TSP), as well as Knapsack problem up to 200 instances. We also empirically show that the designed MONEADD has good scalability when distributed on multiple graphics processing units (GPUs).
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http://dx.doi.org/10.1109/TNNLS.2021.3105937 | DOI Listing |
Brain Lang
January 2025
Key Laboratory of Brain Functional Genomics (MOE & STCSM), Affiliated Mental Health Center (ECNU), Institute of Brain and Education Innovation, School of Psychology and Cognitive Science, East China Normal University, Shanghai 200062, China; Shanghai Changning Mental Health Center, Shanghai 200335, China; Shanghai Center for Brain Science and Brain-Inspired Technology, East China Normal University, China; NYU-ECNU Institute of Brain and Cognitive Science, New York University, Shanghai, China. Electronic address:
Hemispheric specialization of different functions is proposed to confer evolutionary benefits, yet the behavioral impacts of lateralization and its cognitive and neural mechanisms remain unclear. This study investigated the effect of lateralization pattern between language and spatial attention on dual-task performance and its association with callosal connectivity. Functional lateralization was assessed using fMRI verbal fluency and landmark tasks, and interhemispheric connections were evaluated through diffusion-weighted imaging.
View Article and Find Full Text PDFSci Adv
January 2025
Department of Zoology, University of Cambridge, Cambridge, UK.
The evolutionary origin of the vertebrate brain remains a major subject of debate, as its development from a dorsal tubular neuroepithelium is unique to chordates. To shed light on the evolutionary emergence of the vertebrate brain, we compared anterior neuroectoderm development across deuterostome species, using available single-cell datasets from sea urchin, amphioxus, and zebrafish embryos. We identified a conserved gene co-expression module, comparable to the anterior gene regulatory network (aGRN) controlling apical organ development in ambulacrarians, and spatially mapped it by multiplexed in situ hybridization to the developing retina and hypothalamus of chordates.
View Article and Find Full Text PDFElife
January 2025
School of Chemical & Biomolecular Engineering, Georgia Institute of Technology, Atlanta, United States.
Cell identification is an important yet difficult process in data analysis of biological images. Previously, we developed an automated cell identification method called CRF_ID and demonstrated its high performance in whole-brain images (Chaudhary et al., 2021).
View Article and Find Full Text PDFTrends Neurosci
January 2025
Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA. Electronic address:
The evolution of vertebrates from protochordate ancestors marked the beginning of the gradual transition to predatory lifestyles. Enabled by the acquisition of multipotent neural crest and cranial placode cell populations, vertebrates developed an elaborate peripheral nervous system, equipped with paired sense organs, which aided in adaptive behaviors and ultimately, successful colonization of diverse environmental niches. Underpinning the enduring success of vertebrates is the highly adaptable nature of the peripheral nervous system, which is enabled by the exceptional malleability of the neural crest and placode developmental programs.
View Article and Find Full Text PDFSci Technol Adv Mater
December 2024
JST-CREST, Saitama, Japan.
In this review, we present a new set of machine learning-based materials research methodologies for polycrystalline materials developed through the Core Research for Evolutionary Science and Technology project of the Japan Science and Technology Agency. We focus on the constituents of polycrystalline materials (i.e.
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