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Morselized Femoral Head Impaction Bone Grafting of Large Defects in Ankle and Hindfoot Fusions.
Foot Ankle Int
January 2025
Royal National Orthopaedic Hospital NHS Trust, Foot & Ankle Unit, Stanmore, United Kingdom.
Background: Ankle and hindfoot fusion in the presence of large bony defects represents a challenging problem. The purpose of this study was to evaluate outcomes of patients who underwent ankle-hindfoot fusions with impaction bone grafting (IBG) with morselized femoral head allograft to fill large bony void defects.
Methods: This was a 3-center, retrospective review of a consecutive series of 49 patients undergoing ankle or hindfoot fusions with femoral head IBG for filling large bony defects.
Rescue of Interfragmentary Compression in Screw Stripping Failures: The Efficacy of NiTiNOL.
J Foot Ankle Surg
January 2025
Enovis Foot & Ankle, Atlanta, GA; Georgia Institute of Technology, Atlanta, GA. Electronic address:
Orthopedic screws are widely used to achieve bone reduction, compression, and construct stability. However, the relationship between insertion torque, interfragmentary compression, and fixation strength, especially when comparing standard screws with NiTiNOL/sustained dynamic compression (SDC), has not been thoroughly investigated. This study measured insertion torque, interfragmentary compression, and fixation strength for two types of headed orthopedic devices-standard and SDC-using solid foam bone replicates and cadaver validation.
View Article and Find Full Text PDFReconstruction of anterior talofibular ligament and posterior tibiotalar ligament enhance ankle stability after total talus replacement by finite element analysis.
Comput Methods Biomech Biomed Engin
January 2025
Key Laboratory of Advanced Design and Simulation Techniques for Special Equipment, Ministry of Education, Hunan University, Changsha, China.
Total talus replacement has been demonstrated to increase ankle instability. However, no studies have explored how to enhance postoperative stability. This study aims to explore the effect of collateral ligament reconstruction on ankle stability by finite element analysis.
View Article and Find Full Text PDFAn Injectable Oil-Based Depot Formulation of -Acyloxymethyl Prodrug of Ropivacaine for Long-Acting Local Analgesia: Formulation Development and In Vitro/In Vivo Evaluation.
Pharmaceutics
December 2024
School of Pharmacy, Nantong University, 9 Seyuan Road, Nantong 226019, China.
The development of novel long-acting injectables for local anesthetics is necessary to effectively manage the acute postoperative pain. The aim of this study was to prepare an injectable oil-based formulation of ropivacaine (ROP) prodrug (ropivacaine stearoxil, ROP-ST) and to investigate the pharmacokinetics and pharmacodynamics after injectable administration. A novel -acyloxymethyl prodrug of ROP, i.
View Article and Find Full Text PDFIdentifying the Primary Kinetic Factors Influencing the Anterior-Posterior Center of Mass Displacement in Barbell Squats: A Factor Regression Analysis.
Sensors (Basel)
January 2025
Faculty of Sports Science, Ningbo University, Ningbo 315211, China.
Barbell squats are commonly used in strength training, but the anterior-posterior displacement of the Center of Mass (COM) may impair joint stability and increase injury risk. This study investigates the key factors influencing COM displacement during different squat modes.; Methods: This study recruited 15 male strength training enthusiasts, who performed 60% of their one-repetition maximum (1RM) in the Front Barbell Squat (FBS), High Bar Back Squat (HBBS), and Low Bar Back Squat (LBBS).
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