Trigonella foenum-graecum is an annual plant of the genus Trigonella in the Leguminosae family. It is widely distributed in China and has a long history of application. According to phytochemistry research, the seeds, stem, and leaves of this herb contain not only a variety of bioactive ingredients, including alkaloids, saponins, polysaccharides, flavonoids, and phenols, but also abundant nutrients such as unsaturated fatty acids and amino acids and various trace elements. Pharmacological studies have shown that both the extract of T. foenum-graecum and its chemical constituents exhibit hypoglycemic, hypolipidemic, antitumor, antioxidative, antimicro-bial, and hepatoprotective activities. This paper reviews the research progress on the chemical constituents and pharmacological effects of T. foenum-graecum, which may contribute to further development, application, and clinical research of this herb.
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http://dx.doi.org/10.19540/j.cnki.cjcmm.20210430.601 | DOI Listing |
Sci Rep
December 2024
Department of Clinical Pharmacy, Baoshan Hospital Affiliated to, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
This study investigates the potential treatment of breast cancer utilizing Gentiana robusta King ex Hook. f. (QJ) through an integrated approach involving network pharmacology, molecular docking, and molecular dynamics simulation.
View Article and Find Full Text PDFSci Rep
December 2024
Department of Environmental Management and Toxicology, Michael Okpara University of Agriculture, Umudike, Nigeria.
The geochemical and chemical constituents of river water quality could be influenced by human activities and organic processes like water interacting with the lithogenic structure that the river flows through. Evaluating evidence based primary root of the predominant pollutant ions, their interactions as well as the factors controlling their dominance is crucial in studies regarding water environment and hydrology especially as most studies focus on theoretical methods. In order to understand the water cycle, safeguard surface water resources, and preserve the human environment, this study evaluated surface water hydro-chemical facies, quality dynamics, and portability in southern Nigeria using multivariate statistical approaches by analyzing selected hydro-chemical characteristics as indicators of pollution along the river during wet and dry seasons.
View Article and Find Full Text PDFNat Commun
December 2024
School of Materials Science and Engineering, Peking University, Beijing, 100871, China.
Crystal symmetry, which governs the local atomic coordination and bonding environment, is one of the paramount constituents that intrinsically dictate materials' functionalities. However, engineering crystal symmetry is not straightforward due to the isotropically strong covalent/ionic bonds in crystals. Layered two-dimensional materials offer an ideal platform for crystal engineering because of the ease of interlayer symmetry operations.
View Article and Find Full Text PDFArch Razi Inst
June 2024
School of Life Science, Central University of Karnataka, kalaburagi-585367, Karnataka, India.
Nature is a valuable resource, supplying remedies for the treatment of all diseases. Plant kingdom stands for a plethora of natural compounds that are well known for their utilization in therapeutic applications. They may pave the way for the development of new mediators with appropriate efficacy in many pathological disorders in the future.
View Article and Find Full Text PDFJ Ethnopharmacol
December 2024
Xi'an Key Laboratory of Stem Cell and Regenerative Medicine, Institute of Medical Research, Northwestern Polytechnical University, 127 West Youyi Road, Xi'an, Shaanxi 710072, China. Electronic address:
Ethnopharmacological Relevance: The Daqinjiao decoction (DQJT), a classical prescription, has been utilized for millennia in stroke management, yet its underlying mechanisms remained obscure.
Aim Of The Study: The aim of this study was to elucidate the mechanisms through which DQJT mitigates cerebral ischemia/reperfusion injury (CI/RI).
Materials And Methods: The quantification of DQJT's primary components were performed by HPLC.
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