Plant-Derived Essential Oils; Their Larvicidal Properties and Potential Application for Control of Mosquito-Borne Diseases.

Mosquito-borne diseases are currently considered as important threats to human health in subtropical and tropical regions. Resistance to synthetic larvicides in different species of mosquitoes, as well as environmental pollution, are the most common adverse effects of excessive use of such agents. Plant-derived essential oils (EOs) with various chemical entities have a lower chance of developing resistance. So far, no proper classification based on lethal concentration at 50% (LC) has been made for the larvicidal activity of EOs against different species of , and mosquitoes. To better understand the problem, a summary of the most common mosquito-borne diseases have been made. Related articles were gathered, and required information such as scientific name, used part(s) of plant, target species and LC values were extracted. 411 LC values were found about the larvicidal activity of EOs against different species of mosquitoes. Depending on the obtained results in each species, LC values were summarized as follows: 24 EOs with LC < 10 µg/mL, 149 EOs with LC in range of 10- 50 µg/mL, 143 EOs having LC within 50- 100 µg/mL and 95 EOs showing LC > 100 µg/mL. EOs of and against , against , and against and having LC of ~ 1 µg/mL were potentially comparable to synthetic larvicides. It appears that these plants could be considered as candidates for botanical larvicides.