Aim: The aim of the study was to assess bone resorption in patients with chronic generalized periodontitis according to orthopantomogram (OP) and cone-beam computed tomography (CBCT) and substantiate which of these methods is the most appropriate for use.
Materials And Methods: In order to compare the objectivity of the results of examining the periodontal bone tissue by the above methods (panoramic radiography and computed tomography), we analyzed 26 panoramic radiographs and computed tomograms of the same patients, performed on a PICASSO (3D) computed tomograph by «Vatech».
Results: Comparison of CBCT and OP data in patients with periodontal tissue disease showed a significant difference between the indicators of bone tissue resorption in the mesiodistal direction, and revealed that the volumetric image is significantly objective X-ray picture in periodontal diseases by identifying the state (resorption) of the vestibular and oral cortical plates in any section dentition. At the same time, only according to CBCT data, an objective assessment of bone resorption in the vestibulo-oral direction is likely.
Conclusions: Mesiodistal CT and orthopantomographic data do not match well enough. They allow with high accuracy to identify areas of resorption only from the medial and distal sides. However, the vestibulooral CT projection indicates the bias of a two-dimensional image for obtaining an accurate X-ray picture of the state of the alveolar bone and a complete assessment of bone resorption.
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Orthod Craniofac Res
January 2025
Department of Health Sciences, School of Dentistry, Magna Graecia University of Catanzaro, Catanzaro, Italy.
Objective: This retrospective study aimed to evaluate morphometric changes in mandibular condyles of patients with skeletal Class III malocclusion following two-jaw orthognathic surgery planned using virtual surgical planning (VSP) and analysed with automated three-dimensional (3D) image analysis based on deep-learning techniques.
Materials And Methods: Pre-operative (T1) and 12-18 months post-operative (T2) Cone-Beam Computed Tomography (CBCT) scans of 17 patients (mean age: 24.8 ± 3.
Lasers Med Sci
January 2025
Oral Biology Department, Faculty of Dentistry, Suez Canal University, P.O.Box:41523, Ismailia, Egypt.
This study aims to investigate and compare the effects of short and long-term application of low-level laser therapy on the mandibular alveolar process of osteoporotic rats. Forty adult male albino rats were included in this study. After animal grouping, the experimental group received dexamethasone (0.
View Article and Find Full Text PDFCalcif Tissue Int
January 2025
Jerry L. Pettis Memorial VA Medical Center, VA Loma Linda Healthcare System, Loma Linda, CA, USA.
This study assessed the feasibility of miR17 ~ 92-based antiresorptive strategy by determining the effects of conditional transgenic (cTG) overexpression of miR17 ~ 92 in myeloid cells on bone and osteoclasts. Osteoclasts of male and female cTG mutant mice each showed 3- to fivefold overexpression of miR17 ~ 92 cluster genes compared to those of age- and sex-matched wildtype (WT) littermates. Male but not female cTG mutant mice had more trabecular and cortical bones as well as lower bone resorption reflected by reduction in osteoclast number and resorbing surface.
View Article and Find Full Text PDFJ Craniofac Surg
January 2025
Department of Oral and Maxillofacial Surgery, Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Korea.
Osteopetrosis is a rare systemic skeletal disorder characterized by increased bone density and mass resulting from suboptimal or impaired resorption of osteoclastic bone. Compromised bone marrow function and associated disorders of red blood cells contribute to hematopoietic abnormalities, which exacerbate the risk of complex, recurrent infections such as jaw osteomyelitis. This case report describes the treatment of a 68-year-old Korean female with autosomal-dominant osteopetrosis who presented with severe and persistent jaw osteomyelitis complicated by hematopoietic dysregulation.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Growth and Development, University of Nebraska Medical Center, 4000 East Campus Loop South, 68583-0740, Lincoln, NE, US.
Osteogenesis imperfecta (OI) is a fairly common generalized connective disorder characterized by low bone mass, bone deformities and impaired bone quality that predisposes affected individuals to musculoskeletal fragility. Periodontal ligament (PDL)-alveolar bone and PDL-cementum entheses' roles under OI conditions during physiological loading and orthodontic forces remain largely unknown. In addition, bisphosphonates (e.
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