AI Article Synopsis

  • The study investigated the effectiveness of endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) in diagnosing gastric subepithelial lesions (SELs) and aimed to determine the optimal number of needle punctures needed for accurate diagnosis without rapid on-site evaluation (ROSE).
  • A retrospective analysis of 51 patients with 57 SELs showed that EUS-FNB successfully provided a diagnosis for 84% of the lesions, with factors like lesion location and needle type impacting the need for multiple punctures.
  • The findings revealed that two or three needle punctures were optimal for accurate diagnoses, depending on the lesion's location in the stomach and the type of needle used.

Article Abstract

Purpose: The utility of endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) for gastric subepithelial lesions (SELs) has been reported. In this study, we examined the optimal number of needle punctures during EUS-FNB for gastric SELs without rapid on-site evaluation (ROSE). The factors that allowed for a single needle puncture to arrive at the correct diagnosis were also analyzed.

Methods: We conducted a retrospective study of all patients who underwent EUS-FNB to evaluate gastric SELs between April 2015 and September 2020; 51 patients with 57 gastric SELs were enrolled. The optimal number of needle punctures was determined when additional needle passes did not increase diagnostic sensitivity by more than 10%. Factors allowing for only a single needle puncture to arrive at the correct diagnosis were identified by univariate and multivariate logistic regression analyses.

Results: EUS-FNB resulted in a definitive final diagnosis in 48 of 57 lesions (84%). Lesions in the gastric body (odds ratio [OR] 6.15, 95% confidence interval [CI] 1.75-21.6; P < 0.01) and lesions punctured using a 22G Franseen needle (OR 3.61, 95% CI 1.07-12.3; P = 0.04) were independent factors that allowed for only a single needle puncture to arrive at the correct diagnosis. The optimal number of needle punctures for lesions using a 22G Franseen needle in the gastric body and other lesions was two and three, respectively.

Conclusion: The optimal number of needle punctures in EUS-FNB for gastric SELs without ROSE was two or three, depending on the location and type of needle used.

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10396-021-01129-8DOI Listing

Publication Analysis

Top Keywords

optimal number
12
number needle
12
needle punctures
12
gastric sels
12
endoscopic ultrasound-guided
8
ultrasound-guided fine-needle
8
fine-needle biopsy
8
gastric subepithelial
8
subepithelial lesions
8
rapid on-site
8

Similar Publications

From Genetic Findings to new Intestinal Molecular Targets in Lipid Metabolism.

Curr Atheroscler Rep

January 2025

Nantes Université, CHU Nantes, CNRS, Inserm, l'institut du thorax, F-44000, Nantes, France.

Purpose Of Review: While lipid-lowering therapies demonstrate efficacy, many patients still contend with significant residual risk of atherosclerotic cardiovascular diseases (ASCVD). The intestine plays a pivotal role in regulating circulating lipoproteins levels, thereby exerting influence on ASCVD pathogenesis. This review underscores recent genetic findings from the last six years that delineate new biological pathways and actors in the intestine which regulate lipid-related ASCVD risk.

View Article and Find Full Text PDF

Giant encephalocele in newborns: prenatal diagnosis, management and outcome.

Childs Nerv Syst

January 2025

Department of Global Health, Faculty of Health Sciences, McMaster University, 1280 Main St W, Hamilton, ON, L8S 4L8, Canada.

Background: A giant encephalocele associated with Chiari malformation is a rare congenital anomaly from a cephalad neural tube defect. Early prenatal diagnosis and parental counseling are essential; as early surgical intervention can improve outcomes.

Methods: Between 2010 and 2023, twenty-seven newborns out of 43,815 delivered at our institution were diagnosed with encephaloceles, including seven cases of giant encephalocele associated with Chiari malformation type III.

View Article and Find Full Text PDF

Development of an image quality evaluation system for bedside chest X-ray images using scatter correction processing.

Radiol Phys Technol

January 2025

Department of Radiological Sciences, Graduate School of Human Health Sciences, Tokyo Metropolitan University, 7-2-10 Higashi-ogu, Arakawa, Tokyo, 116-8551, Japan.

In plain radiography, scattered X-ray correction processing (Virtual Grid: VG) is used to estimate and correct scattered rays in images. We developed an objective evaluation system for bedside chest X-ray images using VG and investigated its usefulness. First, we trained the blind/referenceless image spatial quality evaluator (BRISQUE) on 200 images obtained by portable chest radiography.

View Article and Find Full Text PDF

Detecting Hemorrhagic Myocardial Infarction With 3.0-T CMR: Insights Into Spatial Manifestation, Time-Dependence, and Optimal Acquisitions.

JACC Cardiovasc Imaging

January 2025

Department of Radiology and Imaging Sciences and Krannert Cardiovascular Research Center, Indiana University School of Medicine, Indianapolis, Indiana, USA. Electronic address:

Background: Hemorrhagic myocardial infarction (hMI) can rapidly diminish the benefits of reperfusion therapy and direct the heart toward chronic heart failure. T2∗ cardiac magnetic resonance (CMR) is the reference standard for detecting hMI. However, the lack of clarity around the earliest time point for detection, time-dependent changes in hemorrhage volume, and the optimal methods for detection can limit the development of strategies to manage hMI.

View Article and Find Full Text PDF

Room-Temperature CsPbI-Quantum-Dot Reinforced Solid-State Li-Polymer Battery.

Small

January 2025

Key Laboratory of Advanced Technologies of Materials, Ministry of Education, School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu, 610031, China.

A novel polymer electrolyte based on CsPbI quantum dots (QDs) reinforced polyacrylonitrile (PAN), named as PIL, is exploited to address the low room-temperature (RT) ion conductivity and poor interfacial compatibility of polymer solid-state electrolytes. After optimizing the content of CsPbI QDs, RT ion conductivity of PIL largely increased from 0.077 to 0.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!