AI Article Synopsis
- Cushing's disease is a serious condition caused by excess production of ACTH due to a pituitary tumor.
- Surgical removal of the tumor is the primary treatment, achieving remission in 65-95% of patients.
- Despite being generally benign, there's a 25-35% chance of the tumor returning, but adjusting surgical techniques can help extend the time before recurrence.
Article Abstract
Cushing's disease is a severe neuroendocrine disorder caused by chronic hypersecretion of ACTH by pituitary adenoma (corticotropinoma). Surgical resection is a gold standard for this disease resulting stable remission in about 65-95% of cases. Despite benign nature of corticotropinoma, recurrence rate is still higher (25-35%) even in specialized neurosurgical centers. Modifications in surgical strategy can prolong recurrence-free period.
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| http://dx.doi.org/10.17116/neiro202185041111 | DOI Listing |
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