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| http://dx.doi.org/10.1002/hon.2916 | DOI Listing |
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ALC-0315 Lipid-Based mRNA LNP Induces Stronger Cellular Immune Responses Postvaccination.
Mol Pharm
January 2025
Ningbo No.2 Hospital, Ningbo, Zhejiang 315010, P. R. China.
At the end of 2019, SARS-CoV-2 emerged and rapidly spread, having a profound negative impact on human health and socioeconomic conditions. In response to this unprecedented global health crisis, significant advancements were made in the mRNA vaccine technology. In this study, we have compared the difference between two SARS-CoV-2 receptor-binding domain (RBD) mRNA-Lipid nanoparticle (LNP) vaccines prepared from two different ionizable cationic lipids: ALC-0315 and MC3.
View Article and Find Full Text PDFAdherence to COVID-19 vaccination during the pandemic and fake news: CorrespondenceAUTHORS' RESPONSEAmostragem e saturação em pesquisa qualitativa: consensos e controvérsiasImpact of the COVID-19 pandemic on the vaccination of children 12 months of age and under: an ecological studyMaranhão A. Missed childhood immunizations during the COVID-19 pandemic in Brazil: analyses of routine statistics and of a national household surveyEffects of the COVID-19 pandemic on routine pediatric vaccination in Brazil.
Rev Bras Enferm
January 2025
Chandigarh University Gharuan, University Centre for Research & Development Department of Pharmaceutical Sciences. Mohali, Punjab, India.
Micro and macropolitical determinants for non-vaccination against COVID-19 in pregnant women in Belo Horizonte.
Rev Bras Enferm
January 2025
Universidade Federal de Minas Gerais. Belo Horizonte, Minas Gerais, Brazil.
Objective: To analyze the determinants for non-vaccination against COVID-19 in pregnant women in Belo Horizonte, Minas Gerais, Brazil.
Methods: An epidemiological study with a cross-sectional design was conducted using data from the project titled "Childbirth and Breastfeeding in Children of Mothers Infected by SARS-CoV-2," developed during the pandemic in the city of Belo Horizonte, Minas Gerais, Brazil.
Results: The study sample consisted of 360 pregnant women, of whom 77.
Dynamics and triggers of misinformation on vaccines.
PLoS One
January 2025
Centro Ricerche Enrico Fermi, Rome, Italy.
The Covid-19 pandemic has sparked renewed attention to the risks of online misinformation, emphasizing its impact on individuals' quality of life through the spread of health-related myths and misconceptions. In this study, we analyze 6 years (2016-2021) of Italian vaccine debate across diverse social media platforms (Facebook, Instagram, Twitter, YouTube), encompassing all major news sources-both questionable and reliable. We first use the symbolic transfer entropy analysis of news production time-series to dynamically determine which category of sources, questionable or reliable, causally drives the agenda on vaccines.
View Article and Find Full Text PDFEstimating SARS-CoV-2 Omicron XBB.1.5 Spike-Directed Functional Antibody Levels From an Anti-Receptor Binding Domain Wuhan-Hu-1-Based Commercial Immunoassay Results.
J Med Virol
January 2025
Microbiology Service, Clinic University Hospital, INCLIVA Health Research Institute, Valencia, Spain.
We investigated whether antibody concentrations measured in plasma using the Roche Elecsys® Anti-SARS-CoV-2 S assay (targeting the receptor binding domain, RBD) could estimate levels of Wuhan-Hu-1 and Omicron XBB.1.5 spike-directed antibodies with neutralizing ability (NtAb) or those mediating NK-cell activity.
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