AI Article Synopsis

  • The study aims to evaluate the use of donor corneal grafts for repairing scleral surface problems in patients whose corneal tissues were not suitable for traditional keratoplasty or were leftover from such surgeries.
  • Retrospective analysis of 16 patients showed various indications for corneal grafts, including trauma, glaucoma surgeries, and implant erosions, with a mean follow-up of 14 months and no reported complications.
  • The results indicate that using these donor grafts effectively restores the ocular surface and improves cosmetic appearance in patients with scleral tissue loss, prompting further investigation into their long-term efficacy and safety.

Article Abstract

Objectives: To investigate the indications for and results of treating scleral surface problems with donor corneal grafts that are not used in keratoplasty surgery or are left over from keratoplasty.

Materials And Methods: The records of 16 patients in whom corneal tissue was used to repair a scleral tissue defect or cover an exposed glaucoma drainage implant were evaluated retrospectively. Partial-thickness grafts were prepared using a combined microkeratome system with artificial anterior chamber in 10 eyes and by manual dissection in 3 eyes. Full-thickness grafts were used in 3 eyes.

Results: There were 8 female and 8 male patients aged 5-79 years (mean: 39.37±24.68). Indications for the use of corneal tissue on the scleral surface were limbal dermoid excision (n=2), pterygium surgery (n=1), intraocular lens removal and scleral fixation intraocular lens (SFIOL) implantation (n=1), exposed SFIOL suture coverage (n=1), trauma (n=2), scleral tissue loss due to repeated glaucoma surgeries (n=5), and exposed glaucoma drainage implant (n=4). The patients were followed for 6-42 months (mean: 14.37±9.14). None of the patients had graft infection, thinning, immunological graft rejection, or vision loss during follow-up. Tectonic lamellar grafts did not adversely affect final visual acuity in any case. At final examination, a good combination of graft and recipient tissue, a smooth ocular surface, and a cosmetic appearance were achieved in all eyes.

Conclusion: Donor corneas that are not suitable for corneal transplantation or left over from the cornea transplant can be used in patients with scleral tissue loss due to various pathologies and in the treatment of glaucoma drainage implant erosion. In these cases, the use of corneal grafts provides a good ocular surface restoration and cosmetic appearance. The effectiveness and safety of this method should be investigated with large patient series and long follow-up times.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8411283PMC
http://dx.doi.org/10.4274/tjo.galenos.2020.27116DOI Listing

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