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Tumor-mutation burden as a marker for immunotherapy of pancreatic cancer: the case report and literature review. | LitMetric

AI Article Synopsis

  • * Standard treatments like palliative chemotherapy and immunotherapy have shown limited effectiveness for this type of cancer.
  • * A case study is presented where a patient with pancreatic cancer improved after receiving a combination of anti-PD-1 immunotherapy and chemotherapy.

Article Abstract

Pancreatic cancer is digestive cancer with limited therapeutic options and a poor outcome. Pancreatic cancer has a high mortality rate, with a 5-year survival rate of less than 5%. The median survival after metastasis of the disease is less than 6 months. Studies have revealed that the standard treatment, including palliative chemotherapy or immunotherapy, is not significantly effective for pancreatic cancer. Herein, we report a case of pancreatic cancer who benefited from a combination of anti-PD-1 immunotherapy and chemotherapy.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670360PMC
http://dx.doi.org/10.1097/CAD.0000000000001232DOI Listing

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