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When the patient can't walk away.
J Med Ethics
January 2025
Rehabilitation Medicine, NHS Lothian, Edinburgh, UK
When the clinician and patient are unable to reconcile differences over treatment, does this mean the latter lacks capacity to decide in such matters? Wellesley analyse the legal judgements in the case of Ms Sudiksha Thirumalesh where, on the particulars, the Court of Protection answered yes, only for the Court of Appeal to disagree. The authors highlight concerns about using isolated false belief as an indicator of incapacity and advise that such matters may be better resolved by greater discussion of the benefits and burdens of treatment, alongside consideration of their costs. Here, I suggest that a disability perspective is also helpful to such cases, recognising that this was a disagreement from which the patient couldn't walk away.
View Article and Find Full Text PDFDo coastal salt mudflats (sabkhas) contribute to the blue carbon sequestration?
Biogeochemistry
January 2025
Environmental Science Center, Qatar University, P.O. Box 2713, Doha, Qatar.
Unlabelled: Blue carbon represents the organic carbon retained in marine coastal ecosystems. (an Arabic for "mudflats"), formed in tidal environments under arid conditions, have been proposed to be capable of carbon sequestrating. Despite the growing understanding of the critical role of blue carbon ecosystems, there is a current dispute about whether sabkhas around the Persian Gulf can contribute to carbon retention as a blue carbon ecosystem.
View Article and Find Full Text PDFAssociation between serum vitamin D and depression among non-alcoholic fatty liver disease.
Asia Pac J Clin Nutr
February 2025
Department of Nursing, Jiangsu Health Vocational College, Nanjing, China. Email:
Background And Objectives: While previous population-based studies have suggested a link between serum vitamin D levels and depression in individuals with non-alcoholic fatty liver disease (NAFLD), the exact correlation between serum vitamin D and depression among NAFLD patients remains controversial and disputed. Thus, we conducted this study to evaluate the relationship between serum vitamin D and depression in NAFLD participants diagnosed via transient elastography.
Methods And Study Design: This cross-sectional study was extracted from the latest NHANES 2017-2018 dataset.
Primary Antibody Deficiencies: Curation Of Gene-Disease Relationships Using A ClinGen Validation Framework.
J Allergy Clin Immunol
January 2025
Nationwide Children's Hospital, Columbus, OH, USA. Electronic address:
Background: The Clinical Genome Resource (ClinGen) is an international collaborative effort between scientists and clinicians, diagnostic and research laboratories as well as the patient community. Using a standardized framework, ClinGen has established guidelines to classify gene-disease relationships as Definitive, Strong, Moderate, and Limited based on available scientific and clinical evidence. When the genetic and functional evidence for a gene-disease relationship has conflicting interpretations or contradictory evidence, they can be Disputed or Refuted.
View Article and Find Full Text PDFHemodynamic Evaluation of Intra-Aortic Dual-Balloon Pump Based on Fluid-Structure Interaction.
Int J Numer Method Biomed Eng
January 2025
Department of Cardiology, First Medical Center, General Hospital of Chinese people's Liberation Army, Beijing, China.
The intra-aortic balloon pump (IABP) is a widely-used mechanical circulatory support device that enhances hemodynamics in patients with heart conditions. Although the IABP is a common clinical tool, its effectiveness in enhancing outcomes for patients with acute myocardial infarction and cardiogenic shock remains disputed. This study aimed to assess the effectiveness of intra-aortic dual-balloon pump (IADBP) and its impact on aortic hemodynamics compared with an IABP.
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