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Measurement of RNA-induced PKR Activation . | LitMetric

Protein kinase R (PKR) is one of the key RNA-activated sensors for innate immunity. PKR is activated by pathogenic or aberrant RNAs such as short double-stranded RNAs or those with imperfect secondary structures, as well as a reduction in the amount and number of RNA modifications. Activation of PKR may be an underlying mechanism for the pathogenesis of human diseases. In this protocol, I describe a method for studying levels of RNA-induced PKR activation .

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376569PMC
http://dx.doi.org/10.21769/BioProtoc.2178DOI Listing

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