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Effect of Yiqi Buxue Decoction on Hemodynamic Changes of the Uterine Artery and Fetal Umbilical Artery and Pregnancy Outcomes in Pregnant Patients with Pulmonary Arterial Hypertension. | LitMetric

AI Article Synopsis

  • The study investigated the impact of Yiqi Buxue decoction on hemodynamic changes in the uterine and fetal umbilical arteries, as well as pregnancy outcomes for pregnant patients with pulmonary arterial hypertension (PAH).
  • 120 patients were randomly divided into two groups; one received routine care with sildenafil citrate, while the other received Yiqi Buxue decoction combined with sildenafil for 6 weeks.
  • Results showed significant improvements in hemodynamics, cardiopulmonary function, and pregnancy outcomes in the group receiving Yiqi Buxue decoction compared to the sildenafil-only group, suggesting its effectiveness in managing PAH during pregnancy.
  • The authors concluded that this decoction could help stabilize hemodynamics and improve

Article Abstract

Objective: To explore the effect of Yiqi Buxue decoction on hemodynamic changes of the uterine artery and fetal umbilical artery and pregnancy outcomes in pregnant patients with pulmonary arterial hypertension (PAH).

Methods: 120 pregnant patients with PAH treated in our hospital (January 2019-January 2020) were chosen as the research objects, and randomly split into group A ( = 60) and group B ( = 60). Both groups received routine treatment, and group B was treated with sildenafil citrate, while group A was treated with Yiqi Buxue decoction combined with sildenafil citrate. Both groups received 6 weeks of treatment to analyze the hemodynamic changes of the uterine artery and fetal umbilical artery and compare the cardiopulmonary function indexes and pregnancy outcomes between the two groups.

Results: The hemodynamic indexes of the uterine artery and fetal umbilical artery, cardiopulmonary function indexes, and pregnancy outcomes in group A after treatment were notably better compared with group B ( < 0.01).

Conclusion: Yiqi Buxue decoction can stabilize the hemodynamics of pregnant patients with PAH, improve their cardiopulmonary function, alleviate hypotension, and thus, reduce the possibility of adverse pregnancy outcomes, which should be popularized in practice.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387161PMC
http://dx.doi.org/10.1155/2021/1849114DOI Listing

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