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| http://dx.doi.org/10.1080/08998280.2021.1930826 | DOI Listing |
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Overview of the Canadian Clinician Investigator Trainees' Research Presented at the 2024 CSCI-CITAC Joint Meeting.
Clin Invest Med
December 2024
Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
The 2024 Annual Joint Meeting (AJM) and Young Investigators' Forum of the Canadian Society for Clinical Investigation (CSCI) and Clinician Investigator Trainee Association of Canada (CITAC) was held on April 11, 2024, in Vancouver, British Columbia. Hosted in collaboration with the University of British Columbia (UBC) and the International Congress on Academic Medicine (ICAM), this meeting marked a significant opportunity for clinician investigator trainees to present their research and connect with national and international peers. The event included 70 trainees, consisting of 58 MD+ (MD/PhD, MD and PhD, MD-MSc, MD and MSc) and 12 Clinician Investigator Program and/or Surgeon-Scientist Training Program trainees.
View Article and Find Full Text PDFCharacterizing Soleus Muscle Response to Targeted Plantar Nerve Modulation Using Mechanomyography.
Neuromodulation
December 2024
Sonostics, Inc, Endicott, NY, USA. Electronic address:
Objective: The human soleus muscles are essential for maintaining cardiac output during upright posture, but age and disuse lead to soleus atrophy, causing numerous health complications in older adults. Here, we investigate the influence of plantar nerve stimulation on soleus muscle activity focusing on ways exogenous stimulation technology can be optimized for the rejuvenation of the soleus muscles.
Materials And Methods: Mechanomyographic (MMG) spectra were obtained to characterize soleus dynamics in adults during quiet sitting.
Navigating Grief in the Realm of Patient Mortality: Insights from Trainee Doctors from a Tertiary Medical Hospital in India- A Qualitative Study.
Indian J Psychol Med
September 2024
Dept. of Psychiatry, Oxford Medical College, Bengaluru, Karnataka, India.
Background: Physician grief, as defined by Kenneth Doka as disenfranchised grief, refers to "the grief that individuals experience when they incur a loss that is not openly acknowledged, publicly mourned, or socially supported." The experience of patient deaths on the emotional health of young doctors is unknown. The after-effects like stress, anxiety, burnout, depression, and others indirectly have a potential impact on decision-making and patient care.
View Article and Find Full Text PDFSimultaneous Protein and RNA Analysis in Single Extracellular Vesicles, Including Viruses.
ACS Nano
October 2024
Department of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, United States.
The individual detection of human immunodeficiency virus (HIV) virions and resolution from extracellular vesicles (EVs) during analysis is a difficult challenge. Infectious enveloped virions and nonviral EVs are released simultaneously by HIV-infected host cells, in addition to hybrid viral EVs containing combinations of HIV and host components but lacking replicative ability. Complicating the issue, EVs and enveloped virions are both delimited by a lipid bilayer and share similar size and density.
View Article and Find Full Text PDFEpidemiological Principles in Claims of Causality: An Enquiry into Repetitive Head Impacts (RHI) and Chronic Traumatic Encephalopathy (CTE).
Sports Med
September 2024
New Zealand Rugby, 100 Molesworth Street, Wellington, New Zealand.
Article Synopsis
- The global sports medicine community is interested in understanding if repetitive head impacts (RHI) lead to chronic traumatic encephalopathy (CTE) and its related clinical syndromes.
- A 2022 article claimed to provide definitive proof of causality between RHI and CTE using the Bradford Hill criteria, sparking significant media attention.
- However, the authors of this counterpoint argue that the evidence is insufficient to support those claims and stress the need for precise definitions, consistent measurements, and well-designed studies before establishing any causal links.
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