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Dementia Care Research and Psychosocial Factors.
Alzheimers Dement
December 2024
UMass Chan Medical School, Worcester, MA, USA.
Background: The deficit of unawareness of cognitive impairment (cognitive anosognosia) is known to be associated with adverse health outcomes, caregiver burden, and worse cognitive outcomes. A better understanding of cognitive self-awareness and the ability to self-judge cognitive performance among the general population would enable a rational design of cognitive screening and improve how subjective cognitive decline and self-reported errors at tasks like medication administration are interpreted.
Method: Participants were enrolled in the Framingham Heart Study, which is a community-based cohort with three generations of participants.
Dementia Care Research and Psychosocial Factors.
Alzheimers Dement
December 2024
Prevent Alzheimer's Disease 2020, Inc., Rockville, MD, USA.
Background: With the changing care landscape for early Alzheimer's disease (AD), optimizing the diagnostic and management process is key. This study assessed the correlation between patient and physician characteristics and outcomes related to the diagnosis, referral, and treatment process for early AD in community-based settings.
Method: This cross-sectional study conducted between August and September 2023 abstracted medical chart data for patients aged 50-89 years who were diagnosed with early AD (mild cognitive impairment [MCI] or mild AD) within the past 2 years and had a clinic visit within the past year.
Dementia Care Practice.
Alzheimers Dement
December 2024
Older Adult's Psychiatry and Psychology Extension Program Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Background: Dementia syndromes are chronic health conditions that lead to significant cognitive decline and functional impairment, including acts of civil life. Concerning the latter, a guardianship petition maybe needed when patients or family are at risk.
Methods: Retrospective cross-sectional study of documentary research on 72 electronical guardianship proceedings involving adults with dementia.
Molecular and Functional Significance of Growth Differentiation Factor-15: A Review on Cardiovascular-Kidney-Metabolic Biomarker.
Curr Cardiol Rev
January 2025
Department of Pharmacology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, 342005, India.
Cardiovascular-kidney-metabolic (CKM) syndrome is the association between obesity, diabetes, CKD (chronic kidney disease), and cardiovascular disease. GDF-15 mainly acts through the GFRAL (Glial cell line-derived neurotrophic factor Family Receptor Alpha-Like) receptor. GDF-15 and GDFRAL complex act mainly through RET co-receptors, further activating Ras and phosphatidylinositol-3-kinase (PI3K)/Akt pathways through downstream signaling.
View Article and Find Full Text PDFRacism and Postpartum Blood Pressure in a Multiethnic Prospective Cohort.
Hypertension
January 2025
Department of Obstetrics and Gynecology, University of Pennsylvania Perelman School of Medicine, Philadelphia. (M.B., O.O., M.M., E.A.H., L.D.L.).
Background: Postpartum hypertension is a key factor in racial-ethnic inequities in maternal mortality. Emerging evidence suggests that experiences of racism, both structural and interpersonal, may contribute to disparities. We examined associations between gendered racial microaggressions (GRMs) during obstetric care with postpartum blood pressure (BP).
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