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| http://dx.doi.org/10.1111/medu.14618 | DOI Listing |
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From Traditional to Cutting-Edge: Transforming Pulmonary Valve Assessment With Advanced Echocardiography Techniques.
Echocardiography
January 2025
Department of Cardiology, German Heart Center Charité, Berlin, Germany.
The pulmonary valve (PV), although often less emphasized than other heart valves, is crucial for cardiac function and hemodynamics. Historically, the PV has been underrepresented in echocardiographic assessments due to its rare involvement in pathological conditions, particularly in adults. Additionally, the anatomical position of the PV makes it one of the most challenging valves to visualize using conventional echocardiography.
View Article and Find Full Text PDFDevelopment of a Thermoresponsive Core-Shell Hydrogel for Sequential Delivery of Antibiotics and Growth Factors in Regenerative Endodontics.
Front Biosci (Elite Ed)
October 2024
Department of Medical Biotechnology, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, 1983969411 Tehran, Iran.
Background: Regenerative endodontics requires an innovative delivery system to release antibiotics/growth factors in a sequential trend. This study focuses on developing/characterizing a thermoresponsive core-shell hydrogel designed for targeted drug delivery in endodontics.
Methods: The core-shell chitosan-alginate microparticles were prepared by electrospraying to deliver bone morphogenic protein-2 for 14 days and transforming growth factor-beta 1 (TGF-β1) for 7-14 days.
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Department of Gastroenterology, University of Balamand, Beirut 3187, Beyrouth, Lebanon.
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View Article and Find Full Text PDFSodium-dependent glucose transporter 2 inhibitors: Transforming diabetic cardiomyopathy management.
World J Cardiol
December 2024
Department of Biochemistry, School of Medicine, College of Medicine, China Medical University, Taichung 404328, Taiwan.
This article addresses the substantial findings of a study on sodium-dependent glucose transporter 2 inhibitors (SGLT2is) and their effects on myocardial function in patients with type 2 diabetes and asymptomatic heart failure. The editorial explores the broader implications of the study findings for clinical practice, thus highlighting the pivotal role of SGLT2is in improving cardiac function, reducing oxidative stress, and attenuating inflammation. It emphasizes the importance of early intervention with SGLT2is in preventing the progression of diabetic cardiomyopathy; hence, these inhibitors have the potential to transform the management of asymptomatic heart failure in patients with diabetes.
View Article and Find Full Text PDFEmpowering healthcare professionals with no-code artificial intelligence platforms for model development, a practical demonstration for pathology.
Discoveries (Craiova)
March 2024
Department of Pathology, Westchester Medical Center, 100 Woods Rd, Valhalla, NY 10595, USA.
Artificial intelligence (AI) and machine learning based applications are thought to impact the practice of healthcare by transforming diagnostic patient management approaches. However, domain knowledge, clinical and coding expertise are likely the biggest challenge and a substantial barrier in developing practical AI models. Most informatics and AI experts are not familiar with the nuances in medicine, and most doctors are not efficient coders.
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