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DPPX antibody-mediated disease mimicking Wernicke's encephalopathy.
BMJ Case Rep
January 2025
Neurology, Joondalup Health Campus, Joondalup, Western Australia, Australia.
Anti-dipeptidyl-peptidase-like protein 6 antibody-mediated disease is a rare autoimmune encephalitis typically presenting with diarrhoea and/or weight loss, central nervous system hyperexcitability and cognitive dysfunction. We present a case of a young woman with 10 days of diplopia and unsteadiness in the context of dysthymia and significant weight loss over 2 months. Initial examination demonstrated mixed dysconjugate nystagmus and ataxic gait.
View Article and Find Full Text PDFA case of ocular flutter associated with sole anti-sulphatide antibody positivity: successful treatment with intravenous immunoglobulin in a pediatric patient.
Acta Neurol Belg
December 2024
Department of Pediatrics, University of Health Sciences, Kartal Dr. Lutfi Kirdar City Hospital, Istanbul, Turkey.
Article Synopsis
- Ocular flutter is a rare neurological disorder marked by fast, irregular eye movements, often linked to autoimmune diseases or infections, yet the specific brain regions involved are still unclear.
- A case study of a 15-year-old male with ocular flutter revealed high levels of anti-sulfatide antibodies, prompting treatment with intravenous immunoglobulin (IVIG), which successfully resolved his symptoms.
- This case highlights the need for sulfatide antibody testing in unusual cases of ocular flutter and suggests that IVIG might be an effective treatment for conditions associated with these antibodies.
Multiple sclerosis presenting with ocular flutter.
Intern Med J
September 2024
Department of Neurology, National Institute of Mental Health and Neurosciences, Bengaluru, India.
Benign Ocular Flutter.
J Pediatr
December 2024
Division of Child Neurology, Department of Neurology and Neurological Sciences, Stanford University, Palo Alto, CA; Division of Neuro-Ophthalmology, Department of Neurology and Neurological Sciences, Stanford University, Palo Alto, CA.
Horizontal Pendular Nystagmus and Ataxia Secondary to Severe Hypomagnesemia.
Tremor Other Hyperkinet Mov (N Y)
July 2024
Neurology Service, University Hospital Marqués de Valdecilla-IDIVAL, Santander, Spain.
Background: Severe hypomagnesemia is an increasingly recognized cause of acute and reversible cerebellar ataxia, often accompanied by cerebellar oculomotor signs such as jerky horizontal or downbeat nystagmus and very rarely ocular flutter.
Phenomenology Shown: This video illustrates horizontal pendular nystagmus in a patient with acute onset cerebellar ataxia associated with severe hypomagnesemia.
Educational Value: Acquired pendular nystagmus can be distinguished from macrosaccadic oscillations and ocular flutter in that the former is composed of two slow phases of equal velocity and the latter of two fast phases of saccadic type with or without intersaccadic interval, respectively.
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