AI Article Synopsis
- Phosphaturic mesenchymal tumors (PMTs) are rare tumors found in soft tissue or bones, associated with a condition called tumor-induced osteomalacia that affects phosphate levels in the body.
- These tumors can be difficult to diagnose due to their varied appearances in imaging and histological studies, which often resemble other similar tumors.
- The paper discusses the imaging characteristics of PMTs and offers a suggested diagnostic approach based on a review of existing literature.
Article Abstract
Phosphaturic mesenchymal tumors (PMTs) are rare mesenchymal neoplasms of soft tissue or bone origin that can give rise to a challenge in diagnostic imaging. These tumors are frequently associated with tumor-induced osteomalacia, also called oncogenic osteomalacia, which is a rare paraneoplastic syndrome characterized by ectopic secretion of fibroblast growth factor 23, a hormone that regulates serum phosphate level. PMTs show polymorphic features on both radiological findings and histological examination, causing problems in diagnosis owing to their similarity with other mesenchymal tumors. Thus, this paper aims to describe radiological aspects of PMTs and suggest an imaging pathway for accurate diagnosis throughout the evidence from the literature review.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8702419 | PMC |
| http://dx.doi.org/10.1007/s11547-021-01412-1 | DOI Listing |
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