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Dissecting Cellulitis Presenting After Hair Restoration Surgery.
Cureus
November 2024
Dermatology, Hospital Universitario "Dr. José Eleuterio González", Nuevo León, MEX.
Dissecting cellulitis (DC) of the scalp is a chronic inflammatory condition marked by neutrophilic cicatricial alopecia, often linked to staphylococcal antigens. This case report details a 34-year-old male with scarring acne who developed DC following follicular unit extraction (FUE) approximately four months prior. Trichoscopic examination revealed brown pigmented dots, erythema, and melicerous crusts.
View Article and Find Full Text PDFThe Potential of Hair-Follicle-Associated Pluripotent (HAP) Stem Cells for Regenerative Medicine.
Methods Mol Biol
December 2024
AntiCancer, Inc., San Diego, CA, USA.
Nestin-expressing hair-follicle-associated pluripotent (HAP) stem cells from mouse and human have been shown to differentiate into neurons, glia, keratinocytes, smooth muscle cells, cardiac muscle cells, and melanocytes in vitro. HAP stem cells have promoted the recovery of peripheral nerve and spinal cord injuries in mouse models by differentiating into glial fibrillary acidic protein (GFAP)-positive Schwann cells. HAP stem cells enclosed on polyvinylidene fluoride membranes (PFM) were transplanted into the severed thoracic spinal cord of nude mice.
View Article and Find Full Text PDFExperimental method for creating skin with acquired appendage dysfunction.
J Dermatol
December 2024
Department of Plastic and Reconstructive Surgery, The University of Tokyo Hospital, Tokyo, Japan.
Mammalian skin appendages, such as hair follicles and sweat glands, are essential for both esthetic and functional purposes. Conditions such as burns and ulcers can lead to dysfunction or loss of skin appendages and result in hair loss and dry skin, posing challenges in their regeneration. Existing animal models are insufficient for studying acquired dysfunction of skin appendages without underlying genetic causes.
View Article and Find Full Text PDFEthical issues of dermatologic medical tourism.
J Am Acad Dermatol
December 2024
Department of Dermatology, University of Connecticut, Farmington, Connecticut; Department of Dermatology, University of Florida, Gainesville, Florida. Electronic address:
Harvest of Vestibular End-Organs under Physiologic Conditions during Labyrinthectomy.
J Vis Exp
November 2024
Department of Otolaryngology - Head & Neck Surgery, Johns Hopkins University School of Medicine.
The living human inner ear is challenging to study because it is encased within dense otic capsule bone that limits access to biological tissue. Traditional temporal bone histopathology methods rely on lengthy, expensive decalcification protocols that take 9-10 months and reduce the types of tissue analysis possible due to RNA degradation. There is a critical need to develop methods to access fresh human inner ear tissue to better understand otologic diseases, such as Ménière's disease, at the cellular and molecular level.
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