AI Article Synopsis

  • The study assesses the effectiveness of an antigen-based nasal screening program for detecting SARS-CoV-2 in Austrian schools, covering over 5,370 schools.
  • By integrating nationwide screening data from March 2021 with a cohort study from 244 representative schools, the results highlight that only a portion of actual infections are identified, indicating low to moderate sensitivity.
  • Conversely, the program shows a very high specificity, as most non-infected individuals tested negative for the virus.

Article Abstract

This study evaluates the performance of the antigen-based anterior nasal screening programme implemented in all Austrian schools to detect SARS-CoV-2 infections. We combined nationwide antigen-based screening data obtained in March 2021 from 5,370 schools (Grade 1-8) with an RT-qPCR-based prospective cohort study comprising a representative sample of 244 schools. Considering a range of assumptions, only a subset of infected individuals are detected with the programme (low to moderate sensitivity) and non-infected individuals mainly tested negative (very high specificity).

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393891PMC
http://dx.doi.org/10.2807/1560-7917.ES.2021.26.34.2100797DOI Listing

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