Four women presented with symptomatic hypercalcaemia and raised concentrations of serum parathyroid hormone (PTH). In each case, serum calcium returned spontaneously to normal. In two patients serum PTH also fell to the normal range and biochemical relapse has not occurred despite prolonged follow-up. In the others, serum PTH remained elevated and subsequent symptomatic hypercalcaemia necessitated parathyroidectomy. In the first two cases, autoparathyroidectomy is the most likely explanation; the initial fall in serum calcium in the other two patients is unexplained. Large fluctuations in serum calcium may occur in some patients with hyperparathyroidism and prolonged and careful observation is required when this occurs.
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http://dx.doi.org/10.1136/pgmj.63.743.741 | DOI Listing |
Objectives: Evaluate the stability of 32 biochemical analytes in venous blood samples stored at 18-25 °C under different time delays prior to centrifugation.
Methods: A prospective study was conducted involving 33 healthy volunteers. Four venous blood samples were collected from each participant.
Front Endocrinol (Lausanne)
March 2025
Department of Urology, Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
Objective: Osteoporosis (OP) and urolithiasis (UL) are two metabolic diseases that are prevalent globally. Previous observational studies have found a relationship between these two diseases that increases the risk of each other, but whether there is a direct causal link is still unclear. Currently, research on the mechanisms of these two diseases mainly focuses on external factors such as diet and environment.
View Article and Find Full Text PDFNutrients
February 2025
Department of Urology, Institute of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan.
: Modern societal stressors have been linked to declining testosterone levels among young men, contributing to somatic, psychological, and sexual health problems. Despite growing evidence suggesting a link between trace elements and testosterone-related symptoms, there are only a few comprehensive analyses on younger populations. This study's aim was to examine how serum trace elements modulate the relationship between testosterone levels and symptom severity.
View Article and Find Full Text PDFNutrients
February 2025
Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, 90127 Palermo, Italy.
In recent years, progress in the field of care has made prematurity an increasingly frequent phenomenon. The premature newborn, due to incompetence, is often subjected to parenteral nutrition (PN) for prolonged periods, and there may be several complications associated with it, first and foremost metabolic complications. In particular, the aim of this study was to evaluate how specific risk factors and/or auxological parameters influenced plasma variations in calcium, phosphorus, and magnesium levels.
View Article and Find Full Text PDFInt J Mol Sci
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Second Department of Neurology, Institute of Psychiatry and Neurology, 02-957 Warsaw, Poland.
MMP-9 and S100B, the proteins involved in blood-brain barrier integrity, are widely studied as biomarkers in many diseases, including epilepsy. They are elevated in epilepsy patients both interictally and following motor seizures. To determine whether motor activity influences their serum concentrations, we investigated the effects of brief, seizure-like physical exercise on serum MMP-9 and S100B levels in healthy individuals.
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